lithocholic acid


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lithocholic acid

[¦lith·ə¦kä·lik ′as·əd]
(biochemistry)
C24H40O3 A crystalline substance with a melting point of 184-186°C; soluble in hot alcohol; found in ox, human, and rabbit bile.
References in periodicals archive ?
Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice.
Those bile acids go to the small intestine and are broken down into secondary bile acids, one of which is lithocholic acid.
Lithocholic acid can break apart DNA strands, form bonds with DNA that disrupt genes, and inhibit DNA repair.
The non-steroidal ligands may be important tools for studying the pharmacology of the receptor, because they may not have the property of bile acids and are not metabolized to form harmful lithocholic acid (Fischer et al.
animals with the toxic endogenous bile acid lithocholic acid led to severe liver damage compared with control animals (Standinger et al.