lobule

(redirected from Liver lobule)
Also found in: Dictionary, Thesaurus, Medical.
Related to Liver lobule: liver acinus

lobule

[′läb·yül]
(biology)
A small lobe.
A division of a lobe.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Hepatic vein: A large vessel that receives blood after it has passed through the central veins of the liver lobules.
AHF were groups of cells smaller than a liver lobule with cytologic changes (clear cell, spindle cell, dysplasia) or changes in staining characteristics.
(4) Hepatocytes in the periportal region of the liver lobule, in contrast, actively produce new glucose, which then is exported into the bloodstream primarily by a different glucose transporter molecule called Glut 2.
Periportal: Referring to the region of a liver lobule adjacent to a branch of the portal vein.
Light microscopy observations of livers from control mice showed a normal morphology with adjacent normal sized sinusoids radiating from the central veins toward the periphery of the liver lobules and a normal portal triad (Figure 3(a)).
Accordingly, we sought to determine (1) whether FVIIIRAg could serve as a reliable immunohistochemical marker for assessing phenotypic change of liver sinusoidal to vascular endothelium, (2) the incidence of FVIIIRAg expression in the liver with progressive stages of fibrosis, and (3) the anatomic sites of FVIIIRAg expression that mark the location of vascular endothelium formation within the liver lobules.
It is recorded that telangiectatic lesions tend to develop either in the top parietal portion of the liver and at the periphery of the liver lobules or in any area of the organ [5,13,14,17,22].
Similarly, slight inflammatory infiltrates in the connective tissue or the glomeruli of the kidneys were observed in single animals, as well as mild turbid swellings in the liver lobules (Table 6).
This is exactly the size of the liver lobules. Those zones may be related to a core of copper accumulated in the center of the lobules.
[1] AIH causes chronic hepatocellular inflammation and necrosis within the liver lobules. This is a response to the body's own immune system attacking liver surface membrane antigens [1] leading to cirrhosis and possibly liver failure.
Infiltration of inflammatory cells was only seen in limited plates, which might be the boundary of liver lobules including the portal areas (Figure 4(d)).