The eosinophils of HES may demonstrate dysmorphism, with increased cell size, [TABULAR DATA FOR TABLE 1 OMITTED] increased nuclear lobation
, or tinged forms, and cytoplasmic vacuolation (Slide 6).
including bronchial isomerism with hyparterial bronchus and unilobar lung may be present.
Bone marrow aspirate smears show atypical mast cells with elongated nuclei, immature chromatin, nuclear lobation
or multinucleation, hypogranular cytoplasm, and excessive cytoplasmic extensions (Figure 1, C).
The nuclei from both sites are round to oval, with occasional cells such as the ones in Figure 4 showing nuclear notching or lobation
. A visible nucleolus is present in both the CTCs and the cells shown from the touch preparation of the original needle biopsy from 4 years prior.