carcinoma

(redirected from lobular carcinoma in situ)
Also found in: Dictionary, Thesaurus, Medical, Acronyms.
Related to lobular carcinoma in situ: invasive lobular carcinoma

carcinoma:

see neoplasmneoplasm
or tumor,
tissue composed of cells that grow in an abnormal way. Normal tissue is growth-limited, i.e., cell reproduction is equal to cell death. Feedback controls limit cell division after a certain number of cells have developed, allowing for tissue repair
..... Click the link for more information.
.
The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/

carcinoma

[‚kärs·ən′ō·mə]
(medicine)
A malignant epithelial tumor.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

carcinoma

Pathol
1. any malignant tumour derived from epithelial tissue
2. another name for cancer
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
Nor is lobular carcinoma in situ (LCIS) simply a risk factor for invasive breast cancer, as has been the traditional view.
Lobular carcinoma in situ was present in the lactiferous sinuses (hematoxylineosin, original magnification X20).
We also queried institutions with regard to which specific lesions they report margin status for, and the results are summarized in Table 8: 778 of 786 respondents (99%) report margins for IC, 783 of 792 (99%) report margins for DCIS, 455 of 723 (63%) report margins for classical lobular carcinoma in situ (LOS), 635 of 723 (88%) report margins for pleomorphic LCIS, 423 of 723 (59%) report margins for other types of "variant" LCIS, 302 of 723 (42%) report margins for atypical ductal hyperplasia (ADH), and 487 of 723 (67%) report margins for "ADH bordering on DCIS."
In particular, the best course of action for "risk factor" diagnoses like atypical lobular hyperplasia or lobular carcinoma in situ, which constituted most of the findings, is even less clear.
The diagnosis and management of pre-invasive breast disease: pathology of atypical lobular hyperplasia and lobular carcinoma in situ. Breast Cancer Res.
Lobular carcinoma in situ most often involves lobules but may also grow along the basement of extralobular ducts, that is, "pagetoid" growth, and may secondarily involve benign lesions, such as radial scars, papillomas, fibroadenomas, and collagenous spherulosis.
One of the 6 lobular carcinoma in situ cases was pleomorphic type (Figure 1, D through F).
Biopsies that showed atypical ductal hyperplasia, atypical lobular hyperplasia, lobular carcinoma in situ, or flat epithelial atypia were grouped as atypical epithelial lesions.
In Situ Lobular Lesions.--Two variants of lobular carcinoma in situ (LCIS)--pleomorphic lobular carcinoma in situ (Figure 3, A and B) (12) and florid LCIS with central necrosis (Figure 3, C and D) (13)--can mimic high-grade DCIS and low-grade DCIS with central necrosis, respectively.
The atypia category included ADH, apocrine atypia, atypical lobular hyperplasia, and classic lobular carcinoma in situ. The carcinoma category included pleomorphic lobular carcinoma in situ, DCIS, and invasive breast carcinoma.
AAA Versus Pleomorphic Lobular Carcinoma In Situ.--The differential diagnosis of AAA includes, in some cases, pleomorphic lobular carcinoma in situ involving sclerosing adenosis (Figure 8, A through C).