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(MIT) 1. To fail. A program loses when it encounters an exceptional condition or fails to work in the expected manner.

2. To be exceptionally unesthetic or crocky.

3. Of people, to be obnoxious or unusually stupid (as opposed to ignorant).

4. Refers to something that is losing, especially in the phrases "That's a lose!" and "What a lose!"
References in periodicals archive ?
But Lost Marbles Ranch (also shown on pages 80 and 81) is flourishing.
Speaking of lost marbles, the Wall Street Journal editors want to intervene in Bosnia "as a training run for how we react if, or when, Russia uses ethnic excuses to lunge at one of its neighbors.