Variations in the natural history and survival of patients with supratentorial
low-grade astrocytomas.
Long-term efficacy of early versus delayed radiotherapy for
low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial.
37) Additionally, alterations in MYB and MYBL1, primarily fusion events, have been observed in angiocentric gliomas and
low-grade astrocytomas.
Pathological and molecular advances in pediatric
low-grade astrocytoma.
Rosenthal fibers and granular bodies, although conceivable in the context of
low-grade astrocytoma, have not been documented to date.
The most common misdiagnosis was
low-grade astrocytoma (39%), followed by nondiagnostic biopsy (18%), highgrade astrocytoma (15%) and, less frequently, oligodendroglioma, infarction, infection, or lymphoma.
18-21) Nakamura et al (20) additionally revealed a strong tendency toward down-regulation of p14ARF protein immunoreactivity during progression from
low-grade astrocytoma to glioblastoma.
Multiple
low-grade astrocytomas may be seen in the spinal cord in the setting of neurofibromatosis type 1.
Low-grade astrocytomas are more common in young adults, whereas high-grade astrocytomas primarily affect older adults.
They located changes in the IDH1 gene in more than 70 percent of three common types of gliomas:
low-grade astrocytomas, oligodendrogliomas, and secondary glioblastomas.
