Ischemia

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ischemia

[i′skē·mē·ə]
(medicine)
Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.

Ischemia

 

a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.

N. R. PALEEV

References in periodicals archive ?
All patients presented with chronic lower limb ischemia with critical limb ischemia.
There were no such observations in respondents with deep vein thrombosis, and only 10% in patients with lower limb ischemia.
In conclusion, new ClearLumen-II automated pulse spray thrombolysis aspiration thrombectomy device in acute lower limb ischemia successfully removed the thrombus without complication and enabled the diagnosis and treatment of chronic atherosclerotic stenosis.
Lower limb ischemia can be caused by a variety of clinical conditions, including critical limb ischemia, abdominal aortic aneurysm, and traumatic arterial injury [1].
Other symptoms associated with a persistent sciatic artery aneurysm include sciatic neuropathy caused by sciatic nerve compression, and lower limb ischemia caused by thrombosis or distal embolization.
Adjuvant fasciotomies were performed in 8 cases of lower limb ischemia who presented after 12 hours and with motor deficit.
Physical examination proved that the left leg was smaller and weaker than the right leg that caused lower limb ischemia. Pulsa-tion of left femoral artery was weak as compared to that of the other leg.
Jones also added that the company is very excited to be making such rapid distribution gains with a company allied closely with ClearStream's strategy for care of lower limb ischemia and related complications associated with diabetes.