lower motor neuron


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lower motor neuron

[′lō·ər ′mōd·ər ‚nü‚rän]
(neuroscience)
An efferent neuron which has its body located in the anterior gray column of the spinal cord or in the brainstem nuclei, and its axon passing by way of a peripheral nerve to skeletal muscle. Also known as final common pathway.
References in periodicals archive ?
Depending on the dose of venom delivered to the patient, the species of snake, and age of the snake, dogs and cats may present with only weakness and ataxia consistent with lower motor neuron blockade.
(8) Electrophysiologic studies can be helpful in identifying active denervation of lower motor neurons. (4,6,7)
Interestingly, adult-onset lower motor neuron disease, progressive external ophthalmoplegia, ptosis, and limb girdle myopathy have also been reported with DGUOK mutations.
In the current reported case, the most likely explanation for the patient's presentation is vancomycin induced myopathy severe enough to cause a lower motor neuron manifestations mounting to severe paralysis.
Thus, the lower motor neurons are the "final common pathway" to coordinate voluntary movement because the lower motor neurons receive information from both UMNs and sensory neurons from the periphery.
Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis.
ALS afflicts both upper and lower motor neurons. The upper motor neurons originate in the brain and brainstem, and the lower motor neurons arise from the spinal cord.
Traditional approaches to diagnose lower motor neuron disorders include creatine kinase (CK) serum quantitation, nerve conduction study electromyogram, and biopsy.
It is common for botox injections to be recommended for this particular aspect of lower motor neuron involvement.
ALS causes upper motor neurons, originating from the top of the brain, and lower motor neurons, originating from the lower part of the brain and the spinal cord, to gradually disintegrate, preventing them from delivering chemical signals and essential nourishment that muscles depend on for normal function.
Motor problems associated with cerebral palsy Motor Problem Site of Injury Spasticity Upper motor neuron (UMN) Dystonia, Athetosis, Ballismus Deep motor neurons (basal ganglia, thalamus Ataxia Cerebellar neurons (cerebellum) Hypotonia Lower motor neuron (LMN)
Significant differences were noted in sex ratio, onset age, ALSFRS-R score, upper motor neuron limb signs, pure lower motor neuron (LMN) bulbar signs, FVC, and survival time between IBP and PBP.

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