lyase


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Related to lyase: Ligases, Isomerases

lyase

[′lī‚ās]
(biochemistry)
An enzyme that catalyzes the nonhydrolytic cleavage of its substrate with the formation of a double bond; examples are decarboxylases.
References in periodicals archive ?
Assay of phenylalanine ammonia lyase enzyme in resistant, moderately resistant and highly susceptible genotypes of groundnut Phenylalanine ammonia lyase (nmol trans-cinnamic acid/ hr/ mg protein) 0 DAI 3 DAI S.
TMS tests: Phenylketonuria, Homocystinura, Maple Syrup Urine Disease, Arginino Succinic Aciduria, Citrullinemia, Propionic Acidemia, Methyl Malonic Acidemia, Isovaleric Acidemia, Beta Ketothiolase deficiency, Glutaric Aciduria types 1 & 2, Medium Chain Acyl-CoA Dehydrogenase deficiency, Very Long Chain Acyl CoA Dehydrogenase deficiency, HMG-CoA Lyase deficiency.
Surprisingly large portions of the genome encode either enzymes of fatty acid metabolism, such as isocitrate lyase, or acidic, glycine-rich polypeptides of unknown function.
Pegvaliase is an investigational study drug that substitutes the deficient PAH enzyme in PKU with the PEGylated version of the enzyme phenylalanine ammonia lyase, to break down Phe.
Polygalacturonase (PG) acts on the pectin chain by adding a water molecule to break the linkage between two galacturonan molecules; Pectin lyase (PL) acts on the galacturonan chain by removing a water molecule from the linkage to break it and to release its products; whereas, Pectin esterase esterifies the pectin by removing methoxy esters (3).
Isozyme of phenyl ammonia lyase were stained by incubating the gels in 1% ABTS solution in 100 mM sodium citrate buffer (pH 6.
Argininosuccinic aciduria (ASAuria; OMIM 207900) is an autosomal recessive inborn error of the urea cycle caused by deficiency of the enzyme argininosuccinate lyase (ASL; EC 4.
The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity.
Many types of marine algae produce a substrate called dimethlysulfoniopropionate (DMSP), which is broken down chemically into dimethyl sulfide (DMS) and acrylate by an enzyme called DMSP lyase.
Galeterone Demonstrates Differentiated Profile with Potent and Selective CYP17 Lyase Inhibition
du Pont de Nemours and Company (Wilmington, DE) has patented a novel tyrosine-inducible tyrosine ammonia lyase enzyme isolated from the yeast Trichosporon cutaneum.
Biochemists discovered the new kind of folding while examining pectate lyase C, a 353-amino-acid bacterial enzyme that causes potatoes, tomatoes, apples, and tropical plants to rot.