lycopus europaeus


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bugleweed

bugleweed

Square-stemmed plant in Mint and Horehound family. Used for hyperthyroid, Graves disease, inhibits iodine metabolism. People with Hypothyroid should not use. Also for coughs, heart(slows and strengthens heart contractions), lung problems, diabetes, Whole plant edible. Astringent, helps stop bleeding, menstruation.
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Keywords: Thyroid function; Hyperthyroidism; Lycopus europaeus (Gypsywort); Urinary [T.sub.3]/[T.sub.4] excretion
Following oral application of an extract of Lycopus europaeus to euthyreotic rats tri-iodothyronine ([T.sub.3]), thyroxine ([T.sub.4]) and thyroid-stimulating hormone (TSH) levels were reduced (Winterhoff et al., 1994).
Patients were excluded from the study if they had taken Lycopus europaeus preparations within the last 3 months, underwent a fasting therapy, took thyroxine preparations and/or thyreostatic drugs, had typical menopause disorders with hot flushes, were pregnant or nursing, had severe forms of hyperthyroidism, thyreotoxic crisis, communication problems or were insufficiently cooperative.
Track I of the study (Lycopus europaeus, n = 33): A Lycopus europaeus preparation (Thyreo-loges N tablets (1)) with a daily dose of 1-0-1 tablets was administered to the patients from V1 to V5.
Track 2 of the study (control, n = 29): These patients were neither administered a Lycopus europaeus preparation nor a "placebo".
The [T.sub.3] excretion in urine did not show a significant difference between control group and Lycopus europaeus group levels.
The univariant variance analysis of the [T.sub.4] excretion in urine verifies a significant interdependency on the 5% significance level between the factors treatment group and time of measurement indicating a difference between control group and Lycopus europaeus group depending on the time of measurement (examination on admission versus examination on discharge) (Table 2).
The [T.sub.4] excretion in urine is increased (p = 0.032) under treatment with Lycopus europaeus (Fig.