Lysergic Acid

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Related to Lysergic Acid: Lysergic acid amide

lysergic acid

[lə′sər·jīk ′as·əd]
(organic chemistry)
C16H16N2O2 A compound that crystallizes in the form of hexagonal plates that melt and decompose at 240°C; derived from ergot alkaloids; used as a psychotomimetic agent.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Lysergic Acid


an organic acid of complex structure (C16H16O2N2) containing an indole residue. Lysergic acid crystals have a melting point of 238°C.

Lysergic acid is found in a number of ergot-generated alkaloids (ergoalkaloids), from which it can be isolated by alkaline hydrolysis. The first complete synthesis of lysergic acid was accomplished in 1954 by R. Woodward. The characteristic biological action of lysergic acid—the contraction of the uterine muscles—is expressed more weakly with lysergic acid itself than with the ergoalkaloids. On entering the organism, lysergic acid diethylamide, known as LSD, is an antagonist of serotonin, a central nervous system regulator. LSD has a strong hallucinogenic effect and is used in the treatment of certain mental diseases.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Although hallucinogens such as lysergic acid diethylamide and psilocybin mushroom have potent psychotic effects, adverse renal effects are also possible.
Participant volume was the lowest for lysergic acid diethylamide (LSD), with a mean of 14 laboratories (Table 1).
We went to parties where we turned on, tuned in and dropped out - although we usually did it with Party Sevens of Watney Bitter rather than the lysergic acid promoted by Timothy Leary.
Chemically known as lysergic acid, it is very similar structurally to a synthetic compound, d-lysergic acid diethylamide (LSD).
Hofmann, in case you didn't know, discovered Lysergic acid diethylamide, better known as LSD or acid.
It all started rather comically, too, when the Swiss research chemist Albert Hofmann accidentally imbibed synthesised lysergic acid diethylamide (LSD).
Always cover marijuana, opiates (heroin and pharmaceuticals), lysergic acid diethylamide (LSD or acid), phencyclidine hydrochloride (PCP or angel dust), psilocybin mushrooms, mescaline, [gamma]-hydroxybutyrate (GHB) and other sedative-hypnotics, 3,4-methylenedioxymethamphetamine (MDMA or ecstasy), and cocaine and other stimulants, including those prescribed for ADHD.
Chemical Warfare Secrets Almost Forgotten is also an excellent resource on the effects of incapacitating chemical agents, with firsthand accounts of human exposure to lysergic acid diethylamide (LSD), 3-quinuclidinyl benzilate (BZ), and other agents.
This condition gradually passed off after about three hours." The chemical he was working with was lysergic acid diethylamide; aka, LSD.
Padilla was given drugs against his will, believed to be some form of lysergic acid diethylamide (LSD) or phencyclidine (PCP), to act as a sort of truth serum during his interrogations."