In June 2019, the Congressionally Directed Medical Research Programs awarded the Company $7.2 million in funding over the course of three years from the Military Infectious Diseases Research Program, United States Army Medical Research and Development Command, to advance its
lysin candidate, CF-296, through IND-enabling studies.
Another phage-derived protein is represented by the virion-associated peptidoglycan hydrolase (VAPGH, or tail-associated
lysin).
The assets purchased include intellectual property for multiple
lysins and for the rapid development of
lysin solutions.
Expression of M6 and M7
lysin in Mytilus edulis is not restricted to sperm, but occurs also in oocytes and somatic tissue of males and females.
Lysin and the vitelline envelope receptor for
lysin in abalone
X-ray crystal structure of the streptococcal specific phage
lysin PlyC.
Lillehoj and her colleagues have identified and applied for a patent for one of the immune molecules, called "NK
lysin."
have signed a contract to support the process development and cGMP manufacture of CF-301, ContraFect's Staphylococcal-specific bacteriophage
lysin. CF-301 is ContraFect's lead compound with potent activity against all forms of Staph infections, including methicillin-resistant (MRSA) and vancomycin-resistant strains (VISA/VRSA).
Among the components found in the plasma of planorbids are lectin,
lysin, agglutinin and substances similar to lymphocin, hydrogen peroxide, as well as other microbian factors (Lie et al., 1980; Boswell and Bayne, 1986; Connors and Yoshino, 1990; Castillo and Yoshino, 2002).
The content of
lysin (5.47 [+ or -] 3.0%) and threonin (15.21 [+ or -] 2.6%) in this protein are higher than in wheat flour protein.
I separated the water, the fats, the oils, the gums, the resins, sugars, starches, pectoses, pentoses, pentosans, legumen,
lysin, the amino and amido acids.
More recent research indicates that a phage bacterial
lysin (PlyG, from phage-[gamma]) can lyse vegetative B.