In June 2019, the Congressionally Directed Medical Research Programs awarded the Company $7.2 million in funding over the course of three years from the Military Infectious Diseases Research Program, United States Army Medical Research and Development Command, to advance its lysin
candidate, CF-296, through IND-enabling studies.
Another phage-derived protein is represented by the virion-associated peptidoglycan hydrolase (VAPGH, or tail-associated lysin
The assets purchased include intellectual property for multiple lysins
and for the rapid development of lysin
Expression of M6 and M7 lysin
in Mytilus edulis is not restricted to sperm, but occurs also in oocytes and somatic tissue of males and females.
and the vitelline envelope receptor for lysin
X-ray crystal structure of the streptococcal specific phage lysin
Lillehoj and her colleagues have identified and applied for a patent for one of the immune molecules, called "NK lysin
have signed a contract to support the process development and cGMP manufacture of CF-301, ContraFect's Staphylococcal-specific bacteriophage lysin
. CF-301 is ContraFect's lead compound with potent activity against all forms of Staph infections, including methicillin-resistant (MRSA) and vancomycin-resistant strains (VISA/VRSA).
Among the components found in the plasma of planorbids are lectin, lysin
, agglutinin and substances similar to lymphocin, hydrogen peroxide, as well as other microbian factors (Lie et al., 1980; Boswell and Bayne, 1986; Connors and Yoshino, 1990; Castillo and Yoshino, 2002).
The content of lysin
(5.47 [+ or -] 3.0%) and threonin (15.21 [+ or -] 2.6%) in this protein are higher than in wheat flour protein.
I separated the water, the fats, the oils, the gums, the resins, sugars, starches, pectoses, pentoses, pentosans, legumen, lysin
, the amino and amido acids.
More recent research indicates that a phage bacterial lysin
(PlyG, from phage-[gamma]) can lyse vegetative B.