macrocycle


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macrocycle

[′mak·rō‚sī·kəl]
(organic chemistry)
References in periodicals archive ?
[sup.1]H NMR (THF-d8, ppm), [delta]: 1.21-1.25 (m, 12H; C[H.sub.3]), 1.80-1.88 (m, 8H; CH2), 2.08-2.16 (m, 8H; CH2), 4.503 (m, 8H; OC[H.sub.2]), 7.45-7.552 (m, 4H; macrocycle), 8.39-8.49 (m, 4H; macrocycle), 8.79-8.90 (m, 4H; macrocycle); IR ([cm.sup.-1]): 2954-2870 (cluster), 1604, 1236, 1089, 1047, 742, UV-Vis (acetonitrile, nm,): 675, 354, MALDITOF (m/z) [[M.sup.+][H.sup.+]] 866.3, elemental analysis: calcd = C (66.54%), N (12.93%), H (5.58%), found: C (66.07), N (13.05%), H (5.70%).
As a result, advanced modification of the macrocycle structure of this compound is being done to improve its efficacy [2].
(1994) A model for the integration of macrocycle and microcycle structure in professional rugby league.
It is noted that we refer to [31-33] for realizing H[infinity]-optimal control through PLC and meanwhile the feedback macrocycle time of motors in physical plant is set to be 5 seconds.
Deli et al., "Age-related responses in circulating markers of redox status in healthy adolescents and adults during the course of a training macrocycle," Oxidative Medicine and Cellular Longevity, vol.
Building the experimental macrocycle to train motocross racers, including the period to take nutritional biocorrectors, provided for some growth of training load.
Appelbaum, "Activity of OPT-80, a novel macrocycle, compared with those of eight other agents against selected anaerobic species," Antimicrobial Agents and Chemotherapy, vol.
It provides testing platform technologies that include MPC biosensor, particle immunofiltration assay, rapid enzymatic assay, minDNA, and synthetic macrocycle complex.
The study took place over the last 6 weeks of the autumn-winter macrocycle. The preparatory training period (12 weeks) was the same for all the participants.
The collaboration is aimed at developing lead orally-bioavailable macrocycle drug to target integrin a4b7, which is involved in the inflammatory process in a number of diseases, most notably for inflammatory bowel disease.
Novel oligosquaramide-based macrocycle (101) as an anticancer agent was prepared and exhibited significant anti- proliferative activity against the NCI-60 human tumour cell line panel, with [IC.sub.50] values ranging from 1 to 10 [micro]M, and was also an effective inhibitor of several important kinases such as ABL1, CDK4, CHK1, PKC, c-MET, FGFR, and others (Villalonga et al.