macrocyclic compound


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macrocyclic compound

[¦mak·rō‚sī ′käm‚pau̇nd]
(organic chemistry)
An organic compound containing a large ring, that is, a closed chain of 12 or more carbon atoms; examples include crown ethers, cryptands, spherands, carcerands, cyclodextrins, cyclophanes, and calixarenes. Also known as macrocycle.
References in periodicals archive ?
The significance of macrocyclic compounds extends from large number of life composing and naturally occurring complexes with enormous biological functions to vast numbers of synthetically made ones for diverse biological and nonbiological functions [19].
To mimic the active site, macrocyclic compounds such as cyclodextrins [1], crown ether [2], cyclophanes [3]and calixarenes [4], each having an inclusion cavity as a basic skeleton of potent artificial monooxygenase, were usually employed.
Zolotov (Ed.) Macrocyclic Compounds in Analytical Chemistry Wiley-Interscience New York (1985) 63.
Again, since macrocyclic compounds are well-known for their ability to show the important property of molecular recognition, macrocyclic systems containing the chalcone moiety are expected to generate compounds having interesting biological and material properties [24, 25].
Macrocyclic compounds, one important group of organic compounds in host-guest chemistry with excellent applications on structural assembly and molecule/ion recognition, on the other hand, can act as guest components for the composites [11].
As reported in the literature [29-32], factors affecting stability of the ionic forms of the macrocyclic compounds, (both cationic and anionic), yielded by proton transfer are electronic factors (or polarization), structural (or steric), and solvation factors.
Porphyrins are tetrapyrrole macrocyclic compounds playing a transcendental role in nature as one of the principal components of molecules such as (i) chlorophyll, (ii) the heme group in blood and cytochromes and (iii) cyanocobalamin (Vitamin [B.sub.12]) [1-3].