macrocyclic compound


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macrocyclic compound

[¦mak·rō‚sī ′käm‚pau̇nd]
(organic chemistry)
An organic compound containing a large ring, that is, a closed chain of 12 or more carbon atoms; examples include crown ethers, cryptands, spherands, carcerands, cyclodextrins, cyclophanes, and calixarenes. Also known as macrocycle.
References in periodicals archive ?
Again, since macrocyclic compounds are well-known for their ability to show the important property of molecular recognition, macrocyclic systems containing the chalcone moiety are expected to generate compounds having interesting biological and material properties [24, 25].
8 December 2009 - US biopharmaceutical company Tranzyme Pharma said today it has inked a strategic collaboration agreement with Bristol-Myers Squibb Company (NYSE: BMY) to discover, develop and commercialise novel macrocyclic compounds directed against targets of interest to Bristol-Myers Squibb.
His group constantly searches for new methods of synthesizing unsaturated macrocyclic compounds, and of modifying their functionality.
Ensemble Therapeutics today announced that preclinical data showing the advantages of novel macrocyclic compounds against challenging drug targets, including its first-in-class, orally active small molecule antagonists of IL-17, will be presented at the Molecular Med Tri Con 2013 Conference being held February 11-15, 2013 in San Francisco, CA.
The project combines the basic ideas of organic chemistry, solid state physics, photochemistry and spectroscopy of metallocomplexes of macrocyclic compounds (MMC) for applications in quantum information processing, sensing, switching and amplification.
Calixarenes are an important class of macrocyclic compounds in supramolecular chemistry, which offer an emerging base/platform for synthesizing new and efficient ligands.