In this measurement, technologists failed to identify microcytes 33 percent of the time, and failed to identify macrocytes
24 percent of the time.
occur in anaemia associated with chronic illness while round target appearing macrocytes
are characteristic of liver diseases such as hepatitis, obstructive jaundice and acute and chronic alcoholism related liver diseases.
Patients with Peripheral smear showing predominant macrocytes
, hypersegmented neutrophils, and clinical features suspected of megaloblastic anemia; like knuckle pigmentation, early graying of hair, dyspepsia, bald tongue along with anemia, proven B12 deficiency biochemically and bone marrow proven megaloblastic anemia were included in the study.
The presence of macrocytes
was not related to changes of plasma osmolality or hyperhydration of red cells.
Presence of megaloblastic anaemia can usually be suspected from examination of peripheral blood with oval macrocytes
being characteristic but examination of bone marrow aspirate is crucial in the diagnoses.
The most common features in blood smears were: polychromatophils, macrocytes
, nucleated red blood cells, teardrop cells, hypogranulation and hypo/hypersegmentation in leukocytes and giant platelets.
9]/L ESR 27 1-30 mm/Hr A few macrocytes
and target cells.
Hematology screening tests included hematocrit, hemoglobin, macrocytes
, and percentage reticulocytes.
The peripheral smear examination showed anisopoikilocytosis with macrocytes
, microcytes, schistocytes, target cells, basophilic stippling, and hypochromia of RBCs.
Due to presence of dual population of cells MCV remains within normal limit or shifts slightly towards higher side if macrocytes
predominate or towards lower side, if microcytes predominate.
MCV [greater than or equal to]110 fL, dysplastic nRBCs, macrocytes