macrolide


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macrolide

[′mak·rə‚līd]
(organic chemistry)
A large ring molecule with many functional groups bonded to it.
References in periodicals archive ?
[USPRwire, Mon Aug 26 2019] Macrolide Antibiotics are bacteriostatic in nature with a broad spectrum of activity against many gram-positive bacteria.
[ClickPress, Tue Aug 27 2019] Macrolide Antibiotics are bacteriostatic in nature with a broad spectrum of activity against many gram-positive bacteria.
Gastrointestinal disturbances, hepatic damages are the common side effects of macrolide antibiotics.
Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolates.
Secondly, due to concerns about macrolide resistance, MPP patients were mostly treated with fluoroquinolone and therefore, we were unable to analyze the effect of macrolide-resistance on prognosis.
- Watertown, Massachusetts-based antibiotic developer Macrolide Pharmaceuticals has been granted a CARB-X award of up to USD 6.8m to support the development of a novel fully synthetic, orally available macrolide antibiotic with Gram-negative activity, with the aim of treating serious infections including drug-resistant complicated urinary tract infections, the company said.
Macrolide resistant bacteria is rapidly increasing in conjunction with the usage of macrolide antibiotics in Japan, and the macrolide resistance rate increased from 10% to 35% in adults from 2008 to 2011 [8].
It is noteworthy that, despite a significant increase in macrolide resistance in some regions, which was a concern at the time the IDSA/ATS guidelines were developed, macrolides still play an important role in CAP therapy (in part because of their coverage of atypical respiratory pathogens).
No association was observed between sex and macrolide or quinolone resistance.
Pneumoniae isolates in the US display in vitro resistance to macrolide antibiotics.
Thirteen patients made full recovery, five of which were treated with a quinolone and macrolide, with the others having either a quinolone or macrolide as part of their treatment.
According to the company, solithromycin is a highly potent next-generation macrolide, the first fluoroketolide, which has potent activity against most macrolide-resistant strains.