For [18F]FDG, the clinically relevant parameter is normally the macroparameter K;; this is usually estimated using linearized Patlak-based graphical methods [18, 19, 31, 32].
Our proposed method allows the estimation of microparameters and the derivation, from them, of the macroparameter [K.sub.i].
However, the mesoparameters of the numerical model were generally adjusted by trial and error until the numerically simulated results corresponded to the macroparameters
of the real specimens.
We also compare the macroparameters
with the results of the simulation.
The microparameters were calibrated through uniaxial compression test to reproduce macroparameters
such as Young's modulus, strain behaviors, and uniaxial compressive strength [24, 25, 48].
In other words, some microparameters must be specified to result in a material with desired macroparameters
such as the uniaxial compressive strength (UCS), Young's modulus, Poisson's ratio, and tensile strength.
A change in the segmental mobility of macromolecules in such a layer is surely bound to affect the macroparameters
of various properties, including the diffusion coefficient of nanocomposites.
At the empirical level, aggregation issues are typically discounted, and the model is estimated as if the microproperties carry over to the macroparameters
. Although this may be unrealistic, data limitations often necessitate such an approach, which does, at least, give some structure and a theoretical basis to the analysis.
The determination of the model parameters is closely related to the rock macroparameters
. Thus, the determined model parameters have certain physical meaning and a wider applicability.
All of these macroparameters
were based on the average values of three specimens.
For the present studies, a general temperature model as proposed by Yamaguchi (27) will be evaluated, regarding macroparameters
(applied normal force and sliding frequency) of the tribological system, rather than incorporating microparameters such as diffusion lengths in both contact bodies and surface roughness profiles (28).