The colorimetric assay results showed that increasing concentrations of MPSE caused reduction in macrophage cell viability.
(11,14,18,19) As a follow-up to those studies, our aim was to investigate the effects of MPSE, which may be considered a potential anti-inflammatory drug, on NO and IL-1[beta] in LPS-induced J774A.1 macrophage cells.
The search query used was 'TS = (macrophage AND polarization).' The timespan was set between the years 2007 and 2016, and the language was set to 'English,' and document type was set to 'article.' The search resulted in 3064 articles that met the inclusion criteria.
There were 3064 articles related to macrophage polarization published between 2007 and 2016.
Translated from Greek as "big eaters," macrophages engulf and digest cellular debris, pathogens and anything else they don't think should be hanging around while also secreting factors that support tissue survival and repair.
After a muscle injury, one class of macrophages shows up on the scene to clear the wreckage left behind, increase inflammation and stimulate other parts of the immune system.
Yamamoto determined that the half-life of the activation effect in an activated macrophage
is approximately six days.
Cell Culture and Bone Marrow-Derived Macrophage
plasticity and heterogeneity give rise to a still opened debate, concerning the nomenclature to identify cell subsets/subtypes undergoing in such different phenotypic, functional (cytokine release), metabolic, regulatory (versus other arms of innate and adaptive immunity) rearrangements.
Working under the direction of Professor Oliver Pabst, researchers from RWTH's Institute of Molecular Medicine have investigated how the functional differences between the various macrophages
Case of tumoral melanosis with a massive infiltration of CD163+ and CD68+ macrophages
. J Dermatol 2018;45:368-70.
These lesions eventually lead to the formation of granulomas (Flat and Moses, 1975) which are inflammatory nodular formations, mainly comprised by macrophages
or histiocytes of dense or loose connective tissue.