major histocompatibility complex


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Related to major histocompatibility complex: human leukocyte antigen

major histocompatibility complex

[′mā·jər ¦hi·stō·kəm′pad·ə′bil·əd·ē ′käm‚pleks]
(immunology)
In vertebrates, a family of genes that encode cell surface glycoproteins that regulate interactions among cells of the immune system, some components of the complement system, and perhaps other related functions connected with intercell recognition. Abbreviated MHC.
References in periodicals archive ?
Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide.
Influence of major histocompatibility complex on reproduction and production traits in swine.
class II alleles and the FVIII inhibitors in Thai hemophilia patients was further investigated in this study, as recent studies have indicated that inhibitor formation depends upon an adequate T-cell response by major histocompatibility complex class II molecules to FVIII resulting from the presentation of FVIII protein antigen to T-cell receptors (18-21).
The correlation between increased tumourigenicity and a decrease in major histocompatibility complex (MHC) Class I expression has been well established.
Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region.
For the assessment of monocyte antigen-presenting capacity, we analyzed 2 genes associated with major histocompatibility complex class II (MHCII), HLA-DRA (major histocompatibility complex, class II, DR alpha) and CD74 (CD74 molecule, major histocompatibility complex, class II invariant chain).
Allovectin-7(r) is a plasmid/lipid complex containing the DNA sequences encoding HLA-B7 and beta-2 microglobulin, which together form a Class I Major Histocompatibility Complex, or MHC-I antigen.
The alphabetized content ranges from historical figures in the field to molecular structures of recently characterized cytokines, the major histocompatibility complex molecules, imunoglobulins, and molecules of related interest to immunologists.
We prefer the scent of people whose major histocompatibility complex - a series of genes in our immune system - is most different from our own.
In a survey, women sniffed men's shirts and preferred the scent of those whose major histocompatibility complex - a series of genes in our immune system - was most different from their own.
The therapy is a highly selective treatment for MS targeting the major histocompatibility complex (MHC) class II molecule to regulate T-cell activity.

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