Hyperthermia

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hyperthermia

[‚hī·pər′thər·mē·ə]
(physiology)
A condition of elevated body temperature.

Hyperthermia

 

the accumulation of excess heat in the body of humans or animals, with an elevation of body temperature, caused by external factors that hinder the transfer of heat to the external environment or increase heat intake from outside the body. Hyperthermia arises when there is maximum strain on the physiological mechanisms of thermoregulation (perspiration, dilation of cutaneous blood vessels, and so forth); if the causes are not removed, it progresses, ending with heat stroke at a body temperature of approximately 41°-42° C.

Hyperthermia is accompanied by an increase of metabolism and qualitative disturbances of it, loss of water and salts, and disruption of blood circulation and the delivery of oxygen to the brain, causing agitation and sometimes convulsions and fainting. High temperature during hyperthermia is tolerated less readily than it is in other feverish diseases. The development of hyperthermia is promoted by an increase in heat production (for example, during muscular work), disruption of thermoregulation mechanisms (with narcosis, drunkenness, and certain diseases), or age-related failure of these mechanisms (in very young children). Artificial hyperthermia is used in treating certain nervous and slowly progressing chronic diseases.

P. N. VESELKIN

References in periodicals archive ?
(12.) Rosero E.B, Adesanya A.O, Timaran C.H, Joshi G.P Trends and Outcomes of Malignant Hyperthermia in the United States, 2000 to 2005.
Lang et al., "Accuracy of malignant hyperthermia diagnoses in hospital discharge records," Anesthesiology, vol.
Micaroni et al., "Characterization and temporal development of cores in a mouse model of malignant hyperthermia," Proceedings of the National Academy of Sciences of the United States of America, vol.
Rosenberg H, Davis M, James D, Pollock N, Stowell K "Malignant hyperthermia".
Benders, "In vitro contraction test for malignant hyperthermia in patients with unexplained recurrent rhabdomyolysis," Journal of the Neurological Sciences, vol.
Mice expressing T48261-RYR1 are viable but exhibit sex-and genotype-dependent susceptibility to malignant hyperthermia and muscle damage.
Preparation of the Datex-Ohmeda Aestiva anesthetic machine for malignant hyperthermia cases.
Unfortunately, the drug did not deliver the same positive result for anesthetic-induced malignant hyperthermia.
Malignant hyperthermia susceptibility: Anaesthetic implications and risk stratification.
(6) Reflexes are normal in anticholinergic syndrome, and are absent or hypoactive in neuroleptic malignant syndrome and malignant hyperthermia. Clonus is not a feature of anticholinergic syndrome, neuroleptic malignant syndrome, or malignant hyperthermia.
One of the most serious complications that can occur with succinylcholine is malignant hyperthermia. Malignant hyperthermia is caused by a genetic defect of muscle metabolism.
Chapters on anesthetic issues address safe airway management, malignant hyperthermia, postoperative nausea, and safe positioning.

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