Hyperthermia

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hyperthermia

[‚hī·pər′thər·mē·ə]
(physiology)
A condition of elevated body temperature.

Hyperthermia

 

the accumulation of excess heat in the body of humans or animals, with an elevation of body temperature, caused by external factors that hinder the transfer of heat to the external environment or increase heat intake from outside the body. Hyperthermia arises when there is maximum strain on the physiological mechanisms of thermoregulation (perspiration, dilation of cutaneous blood vessels, and so forth); if the causes are not removed, it progresses, ending with heat stroke at a body temperature of approximately 41°-42° C.

Hyperthermia is accompanied by an increase of metabolism and qualitative disturbances of it, loss of water and salts, and disruption of blood circulation and the delivery of oxygen to the brain, causing agitation and sometimes convulsions and fainting. High temperature during hyperthermia is tolerated less readily than it is in other feverish diseases. The development of hyperthermia is promoted by an increase in heat production (for example, during muscular work), disruption of thermoregulation mechanisms (with narcosis, drunkenness, and certain diseases), or age-related failure of these mechanisms (in very young children). Artificial hyperthermia is used in treating certain nervous and slowly progressing chronic diseases.

P. N. VESELKIN

References in periodicals archive ?
Urwyler A, Deufel T, McCarthy T, West S; European Malignant Hyperthermia Group.
Characterization of ryanodine receptor-mediated calcium release in human B cells: relevance to diagnostic testing for malignant hyperthermia.
Among this group was a member of the Evans family who has a particularly severe myopathy and was known to have malignant hyperthermia.
Safe duration of postoperative monitoring for malignant hyperthermia susceptible patients.
Preparing a new generation anaesthetic machine for patients susceptible to malignant hyperthermia.
Malignant hyperthermia susceptibility revealed by myalgia and rhabdomyolysis during fluoroquinolone treatment.
1991) demonstrated that a mutation of ryanodine receptor (locus ryr-1) causes malignant hyperthermia in pigs, which leads to PSE meat, numerous studies have been launched into the field of genetic background and major gene identification for meat quality.
No sign of a random malignant hyperthermia attack - a cruel randomness that was hard to stomach for Richard, his best man, and Elizabeth, the maid of honor, as Steven lay fighting for his life in Salem.
Malignant hyperthermia if exposed to anesthesia (a)CNS, central nervous system.
The patient had also experienced two episodes of malignant hyperthermia following induction of general anesthesia.
1), which roughly correspond to the RYR1 regions targeted by mutations causing malignant hyperthermia (MHS1; OMIM 145600) or central core disease (CCD; OMIM 117000) (14-29).
Statin use has been known to trigger symptoms in underlying glycogen storage disease, carnitine palmitoyltransferase deficiency mitochondrial myopathy or malignant hyperthermia.

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