meningioma

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meningioma

[mə‚nin·jē′ō·mə]
(medicine)
A localized tumor composed of meningeal cells, involving the meninges and other central nervous system structures. Also known as meningothelioma.
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Images were analyzed and reported as benign or malignant meningiomas according to DWI using ADC values and then compared with histopathological diagnosis obtained later after tumor resection at the Neurosurgery department of the same hospital.
Lantos, "Malignant meningioma with liver metastases and hypoglycaemia: a case report," Acta Neuropathologica, vol.
There is one recurrence in our study which was a parasagital malignant meningioma which required stage IV decompression.
Biphasic malignant meningioma: a comparative genomic hybridization study.
Different distribution of c-myc and MIB-1 positive cells in malignant meningiomas with reference to TGFs, PDGF, and PgR expression.
MIB-1 labeling indices in benign, aggressive, and malignant meningiomas: a study of 90 tumors.
Continued growth of malignant meningiomas replaces brain tissue by tumor tissue with subsequent proliferation and increasing of malignancy (Shugol et al., 2002).
The knowledge of intratumor molecular heterogeneity is also important considering the possible occurrence of tumor subclones, especially in malignant meningiomas [6, 7].
reported that atypical and malignant meningiomas tend to be markedly hyperintense on diffusion-weighted MR images and exhibit marked decreases in the diffusion constant ( D [sub]av) or apparent diffusion coefficient values when compared with normal brain parenchyma.[sup][17] Although atypical meningioma is diagnosed based on the histological criteria, if the radiological characteristics of a meningioma give the possible diagnosis of atypical meningioma before surgery, neurosurgeons should prepare to remove the tumor completely as possible as they can.
The role of p53 gene mutations in the genesis of meningiomas is controversial (15,16), with a high immunohistochemical expression rate of the mutated protein in atypical and malignant meningiomas but a low rate in benign tumors (17).
Management of atypical and malignant meningiomas: role of high dose 3D-conformal radiation therapy.

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