Marcello Malpighi

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Malpighi, Marcello

(märchĕl`lō mälpē`gē), 1628–94, Italian anatomist. A pioneer in the use of the microscope, he made many valuable observations on the structure of plants and animals. He completed HarveyHarvey, William,
1578–1657, English physician considered by many to have laid the foundation of modern medicine, b. Folkestone, studied at Cambridge, M.D. Univ. of Padua, 1602. Returning to London, he became a physician of St.
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's theory of circulation by his observation of the movement of blood through capillaries and recorded this, as well as his work on the structure of the lung, in De pulmonibus (1661). He is noted also for his studies of the structure of glands and of the brain, spleen, liver, and kidneys; of the anatomy of the silkworm; of the embryology of the chick; and of plant tissues. Several anatomical parts bear his name, including a layer in the human skin and the excretory tubules in insects. He was professor at the Univ. of Bologna (1666–91).


See study by D. B. Meli (2011).

Malpighi, Marcello


Born Mar. 10, 1628, in Crevalcore; died Nov. 30, 1694, in Rome. Italian biologist and physician. Fellow of the Royal Society of London.

Malpighi studied at the University of Bologna, receiving his degree as M.D. there in 1653. He was a professor at the university from 1656 to 1691. Malpighi was one of the founders of plant and animal microscopic anatomy. Using a microscope that magnified up to 180 times, he studied plant anatomy, described the cellular structure of plants (although he did not understand its meaning), discovered the tracheae, established the presence of ascending and descending currents of matter, and discussed the role of leaves in the nutrition of plants. Malpighi described the lymphoid corpuscles of the spleen (Malpighian corpuscles); the renal glomeruli (Malpighian glomeruli); the excretory organs of Arachnida, Myriopoda, and Insecta (Malpighian tubules); the deep layer of the skin (Malpighian layer); blood cells; the alveoli of the lungs; and the taste buds of the tongue. He also discovered capillary circulation.


Opera omnia, vols. 1-2. London, 1687.
Opera posthuma …. London, 1697.


Lunkevich, V. V. Ot Geraklita do Darvina, 2nd ed., vol. 1. Moscow, 1960. Pages 352-67.
Cardini, M. La vita e l’opera di Marcello Malpighi. Rome [1927].


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References in periodicals archive ?
Trehalase2 activity found in the midgut, Malpighian tubules and fat body was 0.
exigua larvae, Tre2 was found highly expressed in the midgut, Malpighian tubules and fat body, but much less so in the brain, cuticle, trachea and testes (Tang et al.
MG, MT, and FB represent the midgut, Malpighian tubules, and fat body, respectively, dissected from adults.
MG, MT, and FB represent midgut, Malpighian tubule, and fat body, respectively, dissected from adults.
The passage of the midgut to the hindgut is characterized by the insertion of Malpighian tubules.
The long, thin Malpighian tubules are composed of a single layer of cuboidal cells, each cell showing a well-developed nucleus with condensed chromatin clumps.
The hindgut--subdivided into ileum and rectum--is responsible for excretion and water reabsorption from food and primary urine produced by Malpighian tubules; thus contributing to the osmotic control of insects (Chapman 1998).
popilliae infections were diagnosed by removing a small portion of Malpighian tubule from each beetle and examining them microscopically for sporophorous vesicles (Andreadis & Hanula 1987).
Total RNA was isolated from different tissues (fat body, gut, Malpighian tubule and trachea of the third instar larvae), 1- and 4-d larvae, using RNeasy[R] Plus Micro Kit with gDNA Eliminator spin column (Qiagen, Hilden, Germany).
The expression levels of BdEcR-Bl in the gut and the Malpighian tubule greatly exceeded those in the trachea and fat body.
In this study, we found that during the last larval stadium, the mRNA transcript of BdEcR-Bl is regulated in a tissuespecific manner in that relatively high amounts of mRNA are found in the gut and Malpighian tubule, and this indicates that the BdEcR-Bl is expressed in a tissue-specific manner, i.