Mandelic Acid

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mandelic acid

[man′del·ik ′as·əd]
(organic chemistry)
C6H5CHOHCOOH A white, crystalline compound, melting at 117-119°C, darkening upon exposure to light; used in organic synthesis.

Mandelic Acid


amygdalic acid, phenylglycolic acid; the simplest aliphatic-aromatic hydroxy acid.

Mandelic acid exists in two optically active forms, ( + ) and ( − ), as well as in the racemic (paramandelic) ( ± ) form. The first two types melt at 133.3°C; the racemic form

melts at 120.5°C. Natural ( − )-mandelic acid occurs in the bitter almond as the glycoside amygdalin, from which it can be extracted by hydrolysis; ( + )-mandelic acid is present (in a bound form) in the fruits and flowers of the common elder; and (±)-mandelic acid is obtained from benzaldehyde:

References in periodicals archive ?
In the neurobehavioral reports, four different measures were used to quantify the level of exposure to styrene: a) concentration of styrene in inhaled air (personal monitors) given as a time-weighted average (TWA), b) concentration of styrene in urine, c) concentration of mandelic acid in urine as a fraction of creatinine in urine, and d) concentration of mandelic acid in urine.
The racemic (+) or (-) mandelic acid was reacted with toluenesulfonic acid and benzene for synthesis using the Dean-Stark trap apparatus.
Biofilms of several gram-negative organisms were reduced by exposure to mandelic acid plus lactic acid (33).