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In developed countries, achalasia of the cardia is diagnosed manometrically by complete absence of primary peristalsis of the oesophageal body, failure of the LOS to relax, and elevated LOS pressure and pressurisation of the oesophagus, both in approximately 50% of cases.
Lysine decarboxylase is usually determined manometrically, as are some other decarboxylases (Gale 1974, Gale and Epps 1944, Najjar 1957, Neuberger and Sanger 1944, Soda and Moriguchi 1969).
[2] Kass et al manometrically verified this finding in humans who had reduced maxillary sinus volume as noted by CT.