lymphoma

(redirected from marginal zone lymphoma)
Also found in: Dictionary, Thesaurus, Medical, Acronyms.

lymphoma,

a cancer of the tissue of the lymphatic systemlymphatic system
, network of vessels carrying lymph, or tissue-cleansing fluid, from the tissues into the veins of the circulatory system. The lymphatic system functions along with the circulatory system in absorbing nutrients from the small intestines.
..... Click the link for more information.
. There are two categories of lymphomas. One type is termed Hodgkin's diseaseHodgkin's disease,
a type of cancer of the lymphatic system. First identified in 1832 in England by Thomas Hodgkin, it is a type of malignant lymphoma. Incidence peaks in young adults and the elderly.
..... Click the link for more information.
, the other, non-Hodgkin's lymphoma (see lymphoma, non-Hodgkin'slymphoma, non-Hodgkin's,
any cancer of the lymphoid tissue (see lymphatic system) in which the Reed-Sternberg cells characteristic of Hodgkin's disease (the other category of lymphoma) are not present.
..... Click the link for more information.
). See also neoplasmneoplasm
or tumor,
tissue composed of cells that grow in an abnormal way. Normal tissue is growth-limited, i.e., cell reproduction is equal to cell death. Feedback controls limit cell division after a certain number of cells have developed, allowing for tissue repair
..... Click the link for more information.
.
The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/

lymphoma

[lim′fō·mə]
(medicine)
Any neoplasm, usually malignant, of the lymphoid tissues.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
A representative case of primary ocular adnexal marginal zone lymphoma with MYD88 L265P mutation and IgM+ plasma cells or plasmacytoid lymphocytes.
[25] not available chronic lymphatic to author leukaemia histology of bladder showed primary splenic marginal zone lymphoma simulating interstitial cystitis Downs et al.
Some lymphoproliferative disorders like CD23 negative chronic lymphocytic leukemia's, CD5 negative mantle cell lymphomas, CD5 positive follicular lymphomas, CD10 negative follicular lymphomas and CD5 positive splenic marginal zone lymphomas also exist and should always be considered in differential diagnosis in appropriate cases.
Conditions covered include acute lymphoblastic leukemia, follicular lymphoma, nodal marginal zone lymphoma, and hairy cell leukemia.
She diagnosed splenic marginal zone lymphoma, and I was treated with Rituxan.
The hematologist performed a bone marrow exam which revealed a large number of CD20 lymphocytes, and she made the diagnosis of splenic marginal zone lymphoma. After treatment with 4 weeks of Rituxan, the spleen returned to normal.
These included 25 cases of MCL, 41 cases of CLL/SLL, 3 cases of hairy cell leukemia, 4 of follicular lymphoma, 5 of diffuse large B-cell lymphoma, 2 of Burkitt lymphoma, 1 of prolymphocytic leukemia B-cell type, 1 of lymphoplasmacytic lymphoma, 5 of acute lymphoblastic leukemia, and 10 cases of marginal zone lymphoma. In addition, 11 blood samples from apparently healthy individuals, 2 blood samples from individuals with infectious mononucleosis, and 1 bone marrow specimen from a patient with benign lymphoid hyperplasia were examined.
The Phase 2 clinical study (CLOVER-1) is in relapsed/refractory (R/R) B-cell malignancies, including multiple myeloma (MM), chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), lymphoplasmacytic lymphoma (LPL), marginal zone lymphoma (MZL), mantle cell lymphoma (MCL), and diffuse large B-cell lymphoma (DLBCL).
TG Therapeutics announced that the Company has confirmed its path to submit umbralisib for accelerated approval based on data from the marginal zone lymphoma cohort of the UNITY-NHL Phase 2b trial.
M2 PHARMA-May 30, 2019-FDA Approves Revlimid In Combination with Rituximab for the Treatment of Adult Patients with Previously Treated Follicular Lymphoma or Marginal Zone Lymphoma
Primary cutaneous marginal zone lymphoma, a variant of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue, most commonly affects the trunk and extremities of middle-aged men (50 years and older).