median lethal dose

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median lethal dose

[′mē·dē·ən ′lēth·əl ′dōs]
(pharmacology)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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In their researches median lethal concentration [LC.sub.50] and median effective concentration [EC.sub.50] values were obtained for algae Selenastrum capricornutum in the range from 224 mg/l to 150 mg/l, Chlorella vulgaris--from 370 mg/l to 63 mg/l, rotifer Brachionus calyciflorus--from 1200 mg/l to 42 mg/l, crustacean Daphnia magna--from 78 mg/l to 10 mg/l, crustacean Thamnocephalus platyurus--from 75.5 mg/l to 33 mg/l, crustacean Artemia salina--from 260 mg/l to 175 mg/l, bacteria Vibrio fischeri--from 42 mg/l to 21.1 mg/l (Zaleska-Radziwill 1997; Sheedy et al.
The 48 h median lethal concentrations (48 h [LC.sub.50]) were predicted by probit analysis as previously reported by Stephan [21].
(5.) Santane JM, Reis AD, Teixeria PC , Ferreira FC, Ferreira CM (2015) Median lethal concentration of formaldehyde and its genotoxic potentials in bullfrog tadpoles.
The first-second instars were the most susceptible, and the median lethal concentrations [[LC.sub.50]] were 4.76, 1.96 and 0.85 mg/L at 24, 48 and 72 h after treatment, respectively.
This study aimed to determine the cell growth of Bti in submerged fermentation process, besides the production of spores and [LC.sub.50] (median lethal concentration) of the preparations obtained, so comparing a standard medium containing a source of nitrogen, the tryptose and another containing a by-product of industrial processing of corn, the soaking corn water ('milhocina').
The corrected mortality was subjected to log-probit regression analysis (12,13) and median lethal concentration ([LC.sub.50]) and 90 per cent lethal concentration ([LC.sub.90]) and associated 95 per cent confidence intervals were calculated.
The variables evaluated were number of live and dead greenhouse whiteflies, and median lethal concentration ([LC.sub.50])
Colony survival assays of the 291.03C cells demonstrate a median lethal concentration (L[C.sub.50]) of arsenite of 0.9 [micro]M and a median lethal dose (L[D.sub.50]) of UVR of 0.05 kJ/[m.sup.2].
The 96-h static bioassay was conducted to estimate the median lethal concentration ([LC.sub.50).