medullary carcinoma


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medullary carcinoma

[mə′dəl·ə·rē ‚kärs·ən′ō·mə]
(medicine)
A form of poorly differentiated adenocarcinoma, usually of the breast, grossly well circumscribed, gray-pink, and firm. Also known as encephaloid carcinoma.
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These cases were histologically reminiscent of medullary carcinoma. In 2 cases, packed tumor cells diffusely infiltrated the breast adipose tissue, often with fine tentacle-like cords.
The medullary carcinomas which are triple negative were excluded from our IHC study which could have contributed to the overall less number of triple negative cases.
Renal medullary carcinoma is a distinctive clinicopathologic entity occurring almost exclusively in young African American men with a sickle cell trait.
For example, if the biopsy tissue contains interface of tumor with normal kidney parenchyma, a thick capsule is often seen in papillary RCC; an infiltrative margin is more frequently seen in high-grade RCC such as clear cell RCC, collecting duct carcinoma, or medullary carcinoma; and a pushing margin is often seen in oncocytoma or chromophobe RCC.
Table 1: Benign and malignant thyroid tumours Pathological diagnosis n = 676 Benign tumours (n = 195) Percent Follicular adenoma 115 59.0% Hurthle cell adenoma 80 41.0% Malignant tumours (n = 481) Papillary carcinoma 298 62.0% Follicular carcinoma 82 17% Medullary carcinoma 40 8.3% Hurthle cell carcinoma 27 5.6% Anaplastic carcinoma 15 3.1% Lymphoma 6 1.3% Metastatic carcinoma 8 1.7% unspecified carcinoma 3 0.6% Malignant teratoma of thyroid 1 0.2% Malignant solitary fibrous tumour 1 0.2% Table 2: Characteristics of patients who had HCNs (n = 107) Parameter Hurthle cell Hurthle cell p-value carcinoma adenoma No.
Rare (new) entities of the breast and medullary carcinoma. Pathology.
In order to avoid misdiagnosis of LELC of the breast, it is important to consider neoplasms of the breast with evident lymphocytic infiltrate, such as lymphomas and medullary carcinomas, in the differential diagnosis.
Regular high-enhancement rings were found mainly in benign nodules, except for one case with medullary carcinoma. This medullary carcinoma was a large heterogeneous mass (5.0 x 3.9 x 4.5 cm) which showed regular shape, defined margin, and rich blood flow signal on conventional US, and internal heterogeneous iso-enhancement pattern and peripheral regular high-enhancement ring were displayed on CEUS.
Medullary carcinoma includes breast tumors with medullary features and is less likely to present at an advanced age.
Grading was not applicable to three tumours; these being medullary carcinoma, metaplastic carcinoma and invasive lobular carcinoma.
* Newly diagnosed medullary carcinoma or anaplastic cancer should be treated without delay.
Twenty-six patients had malignant etiologies as papillary carcinoma (22 patients), medullary carcinoma (2 patients), and follicular carcinoma (2 patients).