with dysmyelintion, spasticity, ataxia, seizures and distinctive neurophysiological findings in two siblings.
Slowly progressive cystic leukoencephalopathy with megalencephaly
in a Japanese boy.
Microcephaly and megalencephaly
are due to disorders of neuronal and glial proliferation or excess or reduced apoptosis.
Hemimegalencephaly and Focal Megalencephaly
in Tuberous Sclerosis Complex.
Human cerebral cortical cell lines from patients with unilateral megalencephaly
and Rasmussen's encephalitis.
Nobody knows what triggers the extra proliferation of immature neurons in unilateral megalencephaly
or what made the girl's cells amenable to life in a culture dish.
Alexander's disease with Megalencephaly
and Periventricular T2 white matter hyperintensities in the bilateral frontal region was seen in one case.
INTRODUCTION: Hemimegalencephaly or unilateral megalencephaly
is a severe, rare and congenital malformation of cortical development, characterized by enlargement of all or parts of a cerebral hemisphere.