megaloblast

Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

Related to megaloblast: macrocytic anemia, macrocyte, pernicious anemia

megaloblast

[′meg·ə·lō‚blast]

(pathology)

A large nucleated erythroblast appearing in bone marrow in vitamin B₁₂ or folic acid deficiency.

Mentioned in ?

References in periodicals archive ?

Diagnosis requires blood tests to look for megaloblasts and measure levels of B12 and folic acid.

MEGALOBLASTIC C ANAEMIA

The earliest sign of folic acid or vitamin [B.sub.12] deficiency is a megaloblastic anemia - so-called because of the abnormal production of megaloblasts, the precursors of mature red cells.

Folate - the "wonder vitamin." (part 1)

Megaloblastic Anaemia- Megaloblasts, Giant Stab and Metamyelocyte in BM Aspirate (100x)

PANCYTOPENIA- A CLINICO-HAEMATOLOGICAL STUDY

The bone marrow aspiration of megaloblastic anaemia showed numerous megaloblasts with large cells with an increased nuclear/cytoplasmic ratio, sieve-like chromatin and giant metamyelocytes (Figure B).

A two years study of showcasing the role of bone marrow aspiration in diagnosing the spectrum of haematological disorders in a tertiary care hospital

MA had typical megaloblasts with sieved chromatin and asynchronic nuclear-cytoplasmic maturation (Figure 1).