megaloblastic anemia

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megaloblastic anemia

[¦meg·ə·lō¦blas·tik ə′nē·m̄e·ə]
(medicine)
Anemia characterized by the occurrence of megaloblasts in the bone marrow and blood.
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Megaloblastic anaemia and aplastic anaemia are important causes of pancytopenia in India.
Findings from the present case study suggest that vitamin B12 deficiency should be considered in the aetiological diagnosis of neurological symptoms in infants, especially in the presence of megaloblastic anaemia and developmental delay.
Complete exclusion of animal foods from girls' meals could lead to vitamin [B.sub.12] deficiency which is likely to result in megaloblastic anaemia, further affecting haemoglobin levels [11].
Anisocytosis is found to be much higher in megaloblastic anaemia as compared to non-megaloblastic anaemia.6
Effect of megaloblastic anaemia on [HbA.sub.2] levels: The patients with normal HPLC were divided in two groups depending upon their MCV values (>110fl) and confirmed by further testing.
Malarial anaemia and nitric oxide induced megaloblastic anaemia: a review on the causes of malarial anaemia.
Diagnostic clues to megaloblastic anaemia without macrocytosis.
Also we can infer that in chronic inflammatory conditions or infections, megaloblastic anaemia can be seen.
It was formerly thought that the neuropathic disease in vitamin B12 deficiency (which can occur without megaloblastic anaemia) would be due to failure of this second enzyme.
Correction of the DNA synthesis defect in vitamin [B.sub.12] deficiency by tetrahydrofolate: evidence in favour of the methyl-folate trap hypothesis as the cause of megaloblastic anaemia in vitamin [B.sub.12] deficiency.
Laboratory diagnosis of megaloblastic anaemia: current methods assessed by external quality assurance trials.
A red, painful tongue can mean megaloblastic anaemia caused by deficiencies of vitamin B12 or folic acid.