melanoblast


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melanoblast

[mə′lan·ə‚blast]
(histology)
Precursor cell of melanocytes and melanophores.
An immature pigment cell in certain vertebrates.
A mature cell that elaborates melanin.
References in periodicals archive ?
Expression of c-kit encoded at the W locus of mice in developing embryonic germ cells and presumptive melanoblasts.
The cancerous cells of melanoma arise from neuroectodermal melanoblasts which would have migrated initially through epidermal dermal junctions of skin, follicles and then to dermis during embryonic development.
It is characterized by the congenital absence of melanocytes in the affected areas of skin and hair, due to mutations of the KIT proto-oncogene, which affects the differentiation and migration of melanoblasts [1].
Nuclei of neoplastic melanoblasts are hyperchromatic, large, with lumpy chromatin and one or more prominent nucleoli.
Melanomas originate from neuroectodermal melanoblasts, which migrate at the beginning of the development period into the epidermal-dermal junction of the skin, follicles, and dermis.
In very early embryogenesis, the first group of neural crest cells gives rise to melanoblasts, which migrate over the surface of the embryo, and from which are derived the fully formed melanocytes.
Melanoma is benign tumour of melanoblasts, the melanin containing cells present in basal layer of epidermis.