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Related to melanoma: Nodular melanoma


see skin cancerskin cancer,
malignant tumor of the skin. The most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. Rarer forms include mycosis fungoides (a type of lymphoma) and Kaposi's sarcoma.
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melanoblastoma; a malignant tumor that consists of melanin-producing cells.

Factors conducive to the development of melanomas include injury and hormonal stimulation, especially during puberty. Melanomas generally occur on the skin; less often, they appear on the retina, pia mater, nasopharynx, larynx, esophagus, and mucosa of the intestine and other organs. Melanomas usually develop at the site of pigmented or depigmented birthmarks, but they may also appear elsewhere. The process starts with a barely perceptible, painless tumor on the skin, sometimes resembling a wart, which gradually becomes dark brown or black. Occasionally, it ulcerates and bleeds. In case of injury, the tumor may enlarge quickly and become tuberous, dense at the base, and stiffer. The regional lymph nodes enlarge. The initial signs that a melanoma is developing at the site of a birthmark are the birthmark’s enlargement, an intensification or reduction in its pigmentation, and the appearance of a red rim around it. Treatment involves prompt surgical intervention, based on early diagnosis, and the use of radiotherapy and drugs to retard the growth and reproduction of the cells.



A malignant tumor composed of anaplastic melanocytes.
A benign or malignant tumor composed of melanocytes.


Pathol a malignant tumour composed of melanocytes, occurring esp in the skin, often as a result of excessive exposure to sunlight
References in periodicals archive ?
The report estimates that almost 13,300 new cases of melanoma will be diagnosed in Australia in 2016, with about 1,800 people dying from the disease.
Primary mucosal melanoma of the sinonasal tract arise de novo from the melanocytes in the surface epithelium or the stroma.
Rapid market growth is also anticipated over the forecast period due to the expanding melanoma treatment population and the continued uptake of recently approved drugs.
Melanoma begins in the melanocytes of the skin, which are the cells that produce a pigment called melanin that colors the skin, hair and eyes.
Since then, the AJCC's Melanoma Staging Committee has been constantly revising the melanoma staging system.
5) As an example, mitotic count is now included as an essential histopathologic element in the newest version of AJCC's melanoma staging and classification system.
The one patient who developed nodular melanoma failed to return for screening for 27 months.
Altogether, the findings suggest that "people with a family history of malignant melanoma are predisposed to malignant melanoma, but not to Parkinson disease," said lead researcher Dr.
Subungual melanoma accounts for 10% of melanoma in black populations and has an equal distribution on the hand and foot.
Furthermore, the majority of claims involving the misdiagnosis of melanoma were because of a false negative diagnosis, which may translate to a reduced chance of survival for some patients, said Dr.
Chromatid breaks indicative of a decreased ability to repair DNA damage caused by UV-B exposure is a factor in the development of basal cell and squamous carcinoma, but not melanoma.
In contrast, melanoma is more associated with acute intermittent doses.

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