melatonin


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melatonin:

see pineal glandpineal gland
, small organ (about the size of a pea) situated in the brain. Long considered vestigial in humans, the structure, which is also called the pineal body or the epiphysis, is present in most vertebrates.
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melatonin

[‚mel·ə′tōn·ən]
(biochemistry)
A hormone secreted by the pineal gland that acts on melanophores in the skins of amphibians and reptiles to concentrate the melanin in the center of the cells, lightening the body surface; in higher vertebrates it conveys information about time that influences reproduction and circadian physiology.
References in periodicals archive ?
In one study, when cancer patients undergoing chemotherapy and radiation took melatonin (20 mg every night) and a melatonin gargle during their seven weeks of treatment, they experienced fewer side effects and were able to tolerate treatment more consistently, compared to a placebo group.
Keywords: Newborn, Hypoxic ischemic encephalopathy, Melatonin, Survival rate.
Relationship between salivary melatonin and severity of periodontal disease.
The amount of melatonin found in foods varies widely by variety, genotype, and growing conditions, so it's difficult to determine how much melatonin you are consuming.
First of all, some people may have a hard time understanding how melatonin can be so important for so many different aspects of the body.
Results: Vancomycin induced massive renal damage (grade III) and led to elevation in biochemical parameters, while melatonin pretreatment prevented the renal damage and the biochemical parameters were also significantly reduced with a p-value of <0.001 for serum urea, creatinine and potassium but had insignificant p-value for serum sodium levels.
After processing, 5-[micro]m thick serial cryosections were prepared using a cryostat to study the effect of melatonin on the number of follicles.
Researchers from the University of Missouri School of Medicine have discovered how melatonin suppresses neurons in the brain that keeps you awake and alert.
The study's author University of Adelaide Professor David Kennaway, who spent four decades studying melatonin, explained its use to treat sleep disorders among children as "alarming."
Melatonin is found in the human skin, but its secretion gradually declines over time, increasing our susceptibility to sleep debt that diminishes the skin's capacity to recover from external insults.
REMfresh is the only seven-hour action melatonin that has been validated in a peer-reviewed pharmacokinetic clinical trial, presented at the international SLEEP 2017 meeting.
Melatonin also protects skin homeostasis, (6) and, consequently, is believed to act against carcinogenesis and potentially other deleterious dysfunctions such as hyperproliferative / inflammatory conditions.