mercaptoacetic acid


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mercaptoacetic acid

[mər¦kap·tō·ə¦sēd·ik ′as·əd]
(organic chemistry)
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To improve the peroxidase-like activity of the np-AuNPs and TEMPO, we assembled mercaptoacetic acid (MA) on the surfaces of np-AuNPs/GCE, and then the 4-carboxy-TEMPO was connected to the mercaptoacetic acid through [Zr.sup.4+] as the bridge bond.
Tan, "One-pot hydrothermal synthesis of water-dispersible ZnS quantum dots modified with mercaptoacetic acid," Journal of Alloys and Compounds, vol.
Fan et al., "A catalysis study of mesoporous MCM-41 supported Schiff base and CuS[O.sub.4] x 5[H.sub.2]O in a highly regioselective synthesis of 4-thiazolidinone derivatives from cyclocondensation of mercaptoacetic acid," Chinese Chemical Letters, vol.
Mercaptoacetic acid modification of the adsorbent led to further enhancement in the removal efficiency of the metal ions by the adsorbent.
A double-disk synergy test was initially performed by using sodium mercaptoacetic acid (SMA) (2) and ceftazidime and meropenem disks (Eiken Chemical Co., Ltd, Tokyo, Japan), and results suggested MBL production.
An equimolar mixture of 6-fluorochroman-2-carbohydrazide 2 (0.01 mol) and different aryl aldehydes (0.01 mol) was taken in RBF and to this, thioglycolic acid (mercaptoacetic acid) (0.29 mol) in toluene was added.
The best results were achieved in an ice-bath thermostated at 4[degrees] C, using mercaptoacetic acid as dispersant.
MBL phenotypic detection was evaluated by the double-disk synergy test (DDST) with imipenem or ceftazidime disks (Oxoid) as substrata, and mercaptopropionic acid (Sigma-Aldrich), mercaptoacetic acid (Sigma-Aldrich), or ethylenediamine tetra-acetic acid (EDTA, Sigma-Aldrich) as MBL inhibitors, according to Picao et al.
A mixture of compound (0.01M) (II) in ethanol (50 mL) and mercaptoacetic acid (0.01 M) with pinch of Zn[Cl.sub.2] was refluxed on a water bath for 8 h.
The metallo-beta-lactamase (MBLs) are carbapenem-hydrolyzing enzyme, MBLs differ from other beta-lactamases in having a serine moiety at the active site and are inhibited by thiol compounds like 2-mercaptoethanol, 2mercaptopropionic acids and mercaptoacetic acid. MBL enzymes require divalent cations for activation (especially [Zn.sup.2-]), are resistant to inhibition by clavulanic acid, sulbactam and tazobactam, are inhibited by chelating agents, and do not hydrolyze monobactam like aztreonam (3).
The particles are rendered water soluble by either treatment with mercaptoacetic acid or the addition of a third outer layer of silica.