acetylcysteine

(redirected from mercapturic acid)
Also found in: Dictionary, Medical.
Related to mercapturic acid: glucuronide, NAPQI

acetylcysteine

[ə‚sed·əl′sis·tē‚ēn or ‚tēn]
(pharmacology)
HSCH2CH(NHCOCH3)COOH Crystals with a melting point of 109-110°C; used as a mucolytic drug.
References in periodicals archive ?
Interestingly, the mercapturic acid metabolite of boscalid was only found in WT males and was almost undetectable in WT females.
Currently, there is no information in the literature about the CEMA/3HPMA ratio or variations in the enzymatic metabolization of acrolein to mercapturic acids among races.
The first enzymatic step in mercapturic acid formation," The Journal of Biological Chemistry, vol.
Voelkel, "Tools in metabonomics: an integrated validation approach for LC-MS metabolic profiling of mercapturic acids in human urine," Analytical Chemistry, vol.
Either it is inactivated by conjugation with glutathione --the major AA scavenger-followed by excretion of mercapturic acids or it is bioactivated to glycidamide through cytochrome P450 2E1 (CYP 2E1)-dependent epoxidation (Bjellaas et al., 2007).
Glutathione conjugation and conversion to mercapturic acids can occur as an intrahepatic process.
The apparent dissociation constants of some glucuronides, mercapturic acids, and related compounds.
We assessed the exposure by measuring the concentrations of styrene in air and in blood and of mandelic acid, phenylglyoxylic acid, 4-vinyl phenol conjugates and regioisomefic phenyl hydroxyethyl mercapturic acids in urine.