Genetic tests, using a blood sample, can analyze the person's genes for particular defects that cause metabolic disease
, but these tests often aren't necessary for diagnosis or for determining treatment.
"The data from these studies provide strong evidence suggesting that low levels of adropin may be an indicator of risk for insulin resistance in obesity and, consequently, an increased risk for metabolic diseases
, including type 2 diabetes," Butler said.
If phthalates are eventually shown conclusively to contribute to obesity or diabetes in men, it's still not clear how these chemicals would affect the opposite sex, since low testosterone has been associated with a lower (not higher) prevalence of metabolic disease
Given Peptimmune's experienced management team, clinical development expertise in both autoimmune and metabolic disease
, and their commitment to moving this program forward, we think they are an excellent partner."
Not only do they "open the door" to new interpretations of obesity's role in inflammation, he says, but they also call attention to the interrelatedness between immunology and metabolic diseases
, such as diabetes.
MedImmune, with 2,500 global staff, is carrying out research in therapeutic areas including respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease
, oncology, neuroscience and infection and vaccines.Country: USASector: BiotechnologyTarget: AlphaCore PharmaBuyer: MedImmune LLC, AstraZeneca PlcType: Corporate acquisitionStatus: Closed
A Clinical Guide to Inherited Metabolic Diseases
, 2nd edition.
The study cannot determine whether lack of sleep causes cardio metabolic disease
or if obesity itself causes sleep disturbances, they said.
Taken together, these results suggest the possibility that therapeutics designed to boost the supply of adropin might be useful in fighting obesity and metabolic disease
Approximately 90% of diabetics suffer from Type II diabetes, the most common metabolic disease
in the world and the seventh-deadliest disease in Canada.
Without t reatment, this metabolic disease
can cause lethargy, stiffness, forgetfulness, madness, coma, and even death.