Obesity is the primary target for prevention and treatment as elevated serum concentration of lipid in obese subjects may lead to severe disturbances (lipotoxicity) and inevitable
metabolic disorder. Adipose tissue is the main organ for lipid storage; however, excess calories will change endocrine functions of adipocytes and the ectopic fat accumulation in peripheral tissues, such as liver, skeletal muscle, pancreatic [beta]-cells, and kidney [11], will lead to lipotoxic stress and low-grade inflammation, accompanied by
metabolic disorder.
(1) National Centre for Inherited
Metabolic Disorders, Temple Street Children's University Hospital, Dublin, Ireland
Keywords: Cirrhosis, Biopsy, Liver,
Metabolic disorders. (JPMA 67: 266; 2017)
A very few hospitals in India have been doing Newborn Screening for
metabolic disorders. Cloudnine Hospitals are among those few hospitals that have been doing this.
"A " At this party, we can see all these"A" At this party, we can see all these children with
metabolic disorders running around with big smiles on their faces.
She suffers from a debilitating
metabolic disorder called mucopolysaccharidosis.
Led by diagnostic services managing director Dr Jamal Golbahar of non-profit Al Jawhara Centre for Genetic Diagnosis and Research, it aims to find out the predominant genetic and
metabolic disorders in Bahrain and encourage the government to introduce a mandatory newborn screening programme.
Receiving a report resulting from such screening is the worst nightmare for a pediatrician--an alphabet soup of
metabolic disorders and lab tests that require a sophisticated clinical Garmin or TomTom GPS system to navigate.
The analysis showed that all components of
metabolic disorder except high blood pressure were more common in the SMD group than in the control group.
Amgen says Cinacalcet HCI represents a potentially significant advance in the treatment of CHD patients diagnosed with SHPT, a common yet serious
metabolic disorder where parathyroid hormone levels are elevated.
The sudden deaths of a mother's three babies were likely to have been caused by an acute
metabolic disorder and not suffocation, a leading expert in sudden infant death told a court yesterday.
Under cross-examination by Paul Dunkels QC, Professor Fleming said that it was likely to be the same
metabolic disorder that had afflicted all three of Patel's children.
