metachromatism

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metachromatism

[¦med·ə′krō·mə ‚tiz·əm]
(chemistry)
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Toluidine blue is a metachromatic vital dye that may bind preferentially to tissues undergoing rapid cell division (such as inflammatory, regenerative, and neoplastic tissue); to the sites of DNA change associated with oral premalignant lesion or both.
Metachromatic leukodystrophy presenting as bipolar disorder.
Similarly, children with metachromatic leukodystrophy are prone to healthcare- and device-associated infections involving opportunistic pathogens, and frequent use of broadspectrum antibiotics may predispose the children for infection with multidrug-resistant bacteria.
Four cases were Metachromatic Leukodystrophy with imaging findings of symmetric periventricular white matter T2/FLAIR hyperintensities with one case showing the typical Tigroid pattern due to sparing of perivascular white matter.
Global Markets Direct's, 'Metachromatic Leukodystrophy (MLD) - Pipeline Review, H1 2016', provides an overview of the Metachromatic Leukodystrophy (MLD) pipeline landscape.
Recently a related illness metachromatic leukodystrophy was treated by Italian scientists using a similar approach, with promising results in patients.
FNAC smears show basaloid cells and metachromatic hyaline material in the form of hyaline spherical globules [Figure 5].
LMP was evaluated by acridine orange (AO), a lysosomotropic base containing metachromatic fluorophore, which becomes charged and retained within acidic compartments [25].