metachromatic leukodystrophy


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Related to metachromatic leukodystrophy: Krabbe disease, adrenoleukodystrophy

metachromatic leukodystrophy

[¦med·ə·krō′mad·ik ‚lü·kə′dis·trə·fē]
(medicine)
A hereditary degenerative disease transmitted as an autosomal recessive, due to sulfatase A deficiency, with excess accumulation of sulfated lipids responsible for metachromasia in various tissues. Abbreviated MLD. Also known as sulfatide lipidosis.
References in periodicals archive ?
Adamsbaum, "Toward a better understanding of brain lesions during metachromatic leukodystrophy evolution," American Journal of Neuroradiology, vol.
Biochemical and genetic analysis of seven Korean individuals with suspected metachromatic leukodystrophy. Ann Lab Med.
(9) Amongst those involving predominantly white matter can be further categorised as predominant involvement of periventricular white matter as in Metachromatic leukodystrophy, Classic X-linked adrenoleukodystrophy, Globoid cell leukodystrophy (Krabbe disease), vanishing white matter disease and those with predominant subcortical white matter involvement as Van Der Knaap disease.
* The report provides a snapshot of the global therapeutic landscape of Metachromatic Leukodystrophy (MLD)
Metachromatic leukodystrophy affects the nervous system.
Key Words: Metachromatic leukodystrophy, brain plasticity, traumatic brain injury, electrophysiologic studies, rehabilitation, MRI
The future for treatment by bone marrow transplantation for adrenoleukodystrophy, metachromatic leukodystrophy, globoid cell leukodystrophy and Hurler syndrome.
Emily Hart, from Netherton, Dudley, died in December 2006 of a rare disorder, metachromatic leukodystrophy, which left her unable to walk or even swallow.
If the reader allows him or herself to look beyond the minutiae of Austin's particular scientific research interests (e.g., metachromatic leukodystrophy or mucopolysaccharidosis VI), he or she will appreciate the author's resolve and apparent belief that personal identity, as much as scientific rigor, is what makes for creative and successful scientific research.
His determination has benefited a number of charities, including the hospice that cared for his late granddaughter Emily, who died from metachromatic leukodystrophy, aged just five.
His determination has benefited a number of charities, including the hospice that cared for his late grandaughter Emily, who died from metachromatic leukodystrophy, at just five..
Tim DeLage, whose son Devon was born with a rare degenerative disorder called metachromatic leukodystrophy and died at 2' years old April 3, said the hospice program made a huge difference in the quality of his son's short life as well as the ability of family members to accept Devon's death.