Nguyen, A catalytically active, permanently microporous MOF with metalloporphyrin
As mentioned above, Cl[sub]2 toxicity is mainly caused by oxidative stress to tissues; thus, antioxidants including dimethylthiourea, compound AEOL 10150 (a metalloporphyrin
catalytic antioxidant), N-acetyl cysteine, aerosolized ascorbate, and deferoxamine  have been shown to alleviate Cl[sub]2-induced injury in animal models of different species.
Protection by a Metalloporphyrin
Superoxide Dismutase Mimetic against Signs of Dry-eye Disease
This higher complexity of tetraazamacrocyclic ligands, specifically porphyrin ligands or porphyrin derivatives, such as chlorins, has several causal factors, one of the most relevant being the significant flexibility of the porphyrin ring, which can generate a series of spatial conformations Which have been studied in different metalloporphyrins
, which has been studied in both metalloporphyrin
complexes alone and in heme groups in several hemoproteins [24-28].
Huie, "Salting-out surfactant extraction of porphyrins and metalloporphyrin
from aqueous non-ionic surfactant solutions," Talanta, vol.
Xiong, "Antioxidant activity of conjugation of metalloporphyrin
combining with bovine serum albumin," Science China Chemistry, vol.
Liu, "Spectroscopy on the interaction between four metalloporphyrin
complexes and serum albumin," Chemical Reagents, vol.
This phenomenon might be attributed to a deep change in structure and morphology of the metalloporphyrin
due to axial ligation of the analyte.
A redox-active metalloporphyrin
, BMX-001, was shown to enhance islet viability, reduce apoptosis in vitro, and improve marginal islet mass engraftment in diabetic mouse models .
Bai et al., "Potent metalloporphyrin
peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction," Circulation, vol.
Liu, "Temporal and spatial profiles of cell loss after spinal cord injury: reduction by a metalloporphyrin
," Journal of Neuroscience Research, vol.
Haem enters the enterocyte as a metalloporphyrin
. Within the cell, iron is released from haem by haem oxygenase to pass into the body as inorganic iron.