9 Platelets * * * Mean Platelet Volume * * * Neutrophils 7 29 58 Bands 54 50 35 Lymphocytes 10 9 5 Monocytes 7 0 2 Metamyelocyte
12 9 0 Myelocyte 8 2 0 Promyelocyte 2 1 0 Nucleated Red Blood Cells 2 0 2 Polychromasia present [dagger] [dagger] Poikilocytosis present [dagger] present Anisocytosis present [dagger] present Microcytes present [dagger] [dagger] Spherocytes present [dagger] [dagger] Mega-thrombocytes present present [dagger] Absolute Neutrophils 3.
8) Positive smears were determined following the criteria of the consensus group: red blood cell (RBC) morphology of either 2+/moderate or greater; any positive finding related to malaria; platelet morphology (giant platelets) of either 2+/moderate or greater; platelet clumps more frequent than rare/occasional; Dohle bodies, toxic granulation, or vacuoles of either 2+/moderate or greater; and presence of abnormal cell types (blast [greater than or equal to]1, metamyelocyte
>2, myelocyte/ promyelocyte [greater than or equal to]1, atypical lymphocytes >5, nucleated RBC [greater than or equal to] 1, and plasma cells [greater than or equal to]1).
In the aspiration smear, 18% myelocyte, 35% metamyelocyte
, 11% polymorphonuclear leukocyte, 28% lymphocyte, 2% normoblast, 1% monocyte, 1% eosinophil, and 4% lymphoblast-like cells were present.
The College of American Pathologists defines a band neutrophil (stab or staff cell) as follows: "Bands are the same size or slightly smaller than metamyelocytes
were present in 5 cases (29%).
9]/L with 62% neutrophils, 14% stab cells, 6% metamyelocytes
, 4% myelocytes, and 14% lymphocytes; mean corpuscular volume, 87 fL; and platelet count, 415x[10.
Moreover, occasional metamyelocytes
and nucleated red blood cells were also noted.
Maturation occurs in a post-mitotic compartment, and is made up of metamyelocytes
, band forms and mature neutrophils, and allows the cells to reach full functional state prior to the release into the circulation: also called the labile compartment or pool.
2 %) Platelets (thou/ul) 180 (140-450 THO/UL) Neutrophils (%) 33 (40-75 %) Lymphocytes (%) 64 (20-45 %) Eosinophils (%) 0 (1-6 %) Metamyelocytes
(%) 1 (0) Monocytes (%) 2 (4-13 %) Basophils (%) 0 (0-1%) PT (sec) 20.
HL-60 promyelocytic leukemia cells (passage number between 2 and 10) were differentiated into metamyelocytes
using DMSO to enable production of higher levels of [LTB.
Dysplastic changes seen included the presence of giant metamyelocytes
and giant banded heterophils.
The most frequently infected blood cells are monocytes, however, infections in other cell types have been described, including lymphocytes, atypical lymphocytes, promyelocytes, metamyelocytes
, and band and segmented neutrophils (10,35-37).