Dolovich, "Emitted doses of salbutamol pressurized
metered-dose inhaler from five different plastic spacer devices," Fundamental & Clinical Pharmacology, vol.
The deposition pattern of inhaled drug is determined by multiple factors including the device used, aerosol formulation, particle size, use of a spacer, especially with
metered-dose inhalers (MDI) and the patient's inhalation technique.1 Press-and-breathe MDIs and dry-powder inhalers (DPIs) are the most commonly used delivery devices for administering aerosolised drugs.
A comparison of albuterol administered by
metered-dose inhaler and spacer with albuterol by nebulizer in adults presenting to an urban emergency department with acute asthma.
Evaluation of the effect of a large volume spacer on the systemic bioactivity of flucatisone propionate
metered-dose inhaler. Chest, 116(4), 935-940.
Continue to inhale deeply and hold breath for 10s MDI,
metered-dose inhaler.
Mene Pangalos, Executive Vice President, BioPharmaceuticals R&D, said: As the first medicine in its class to be approved in a pressurised
metered-dose inhaler in Japan, Bevespi Aerosphere offers an important new treatment option and choice of inhaler device for patients with moderate to very severe chronic obstructive pulmonary disease.
The company also plans to evaluate ensifentrine in a
metered-dose inhaler formulation as part of a comprehensive clinical program intended to fully demonstrate the clinical utility of ensifentrine in improving the standard of care for COPD.
The product is administered intranasally via a pressurized
metered-dose inhaler and is intended to be used to restore the normal physiologic activity of the Eustachian tube, which is the small tube that connects the middle ear to the back of the nasopharynx.
Alvesco is an inhaled anti-inflammatory maintenance therapy and is delivered by a
metered-dose inhaler to help control persistent asthma.
A comparison of breath-actuated and conventional
metered-dose inhaler inhalation techniques in elderly subjects.
Roche, "Misuse of corticosteroid
metered-dose inhaler is associated with decreased asthma stability," European Respiratory Journal, vol.
Currently, three combinations of inhaled corticosteroid plus long-acting beta-agonists are available for the treatment of COPD, but not this particular combination of mometasone furoate with formoterol fumarate administered with a
metered-dose inhaler, which is licensed for asthma treatment in the United States under the name Dulera, Dr.
