antifungal agent

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Related to miconazole: ketoconazole, nystatin, miconazole nitrate

antifungal agent

[‚an·tē′fəŋ·gəl ‚ā·jənt]
(materials)
A chemical compound that either destroys or inhibits the growth of fungi.
References in periodicals archive ?
Yeast colony inoculum was evenly cultured onto SDA media and after that ketoconazole, fluconazole, and miconazole disc placed on the media surface.
In 2013, Miconazole cream was approved as a treatment for adults, and it is the first topical azole antifungal agent approved to treat tinea cruris and tinea corporis with a one-week, once-daily treatment regimen, according to the company release.
A clinical double-blind trial of topical miconazole and clotrimazole against superficial fungal infections and erythrasma.
The objective of the present study was to develop a simple, less time-taking, and cheap extractive spectrophotometric method for routine analysis of miconazole nitrate in pharmaceutical preparations.
Drug susceptibility was assessed using FUNGITEST[R] (Sanofi Diagnostics Pasteur) for the analysis of fungal growth in the presence of six drugs, such as 5-fluorocytosine, amphotericin B, miconazole, ketoconazole, itraconazole and fluconazole used at two concentrations, in modified RPMI 1640 medium, in the presence of a redox indicator.
Thus, the objectives of the study were to test the EPPAF mucoadhesive formulation efficacy, as well as its safety, acceptability, and anti-Candida activity compared to miconazole oral gel (20 mg/g), through the quantification and identification of isolated Candida species of the mucosa of the population studied before and after treatments.
Further, the new materials showed sustained drug release and provided antifungal effects for weeks (in case of chlorhexidine digluconate) to month (in case of miconazole) and also made the specimens disc capable of being charged again.2
Final drug concentrations of 12.5-0.1 [micro]g/mL for miconazole and of 12.5-0.05 [micro]g/mL for macelignan were obtained.
He recorded a narrative verdict saying death "may have been contributed to by combined use of warfarin and miconazole".
Miconazole ear drops were also used as treatment in 25 patients of which 14 patients (56%) got cured, 5 patients (20%) showed improvement, 3 patients (12%) did not respond, 3 patients did not come for follow up.
From there, the researchers found that miconazole and clobetasol performed best within the respective classes.