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Broad-spectrum microbicidal activity, toxicologic assessment, and materials compatibility of a new generation of accelerated hydrogen peroxide- based environmental surface disinfectant.
For the minimum microbicidal concentration (MMC) determination, 10 [micro]l aliquots from each well that showed no growth of microorganism were plated on Mueller-Hinton Agar or Sabouraud Dextrose Agar and incubated at 37[degrees] C for 24 h (bacteria), 48 h (Candida spp.), and 72 h (Cryptococcus).
The dominant nitrogen [N.sub.2] bands were detected; the lower intensity of [N.sup.+.sub.2] indicates the high electron temperature important for microbicidal activity [44, 45]; also the minute peak attributed to OK was detected.
Interestingly, because clinical forms are studied in this work, where the in situ immune response pattern is different, the activation of the UPR pathway probably can be a determinant for the control of bacillary proliferation or the microbicidal response.
Binding of IFN-[gamma] to the cell surface receptor can promote microbicidal activity and proinflammatory cytokine production via the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway [27, 74, 75].
IFN-[gamma] treatment activates the production of NO in macrophages, which is the main microbicidal molecule involved in the control of M.
Key features include broad and rapid microbicidal activity against gram-positive and gram-negative bacteria (including multidrug resistant strains), as well as yeast; surfactant properties for enhanced anti-biofilm effects; and easy removal by irrigation and bioresorbability when left in place.
Paint Shield is an Interior microbicidal latex paint.
The minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) were determined using the microdilution technique proposed by CLSI (2005).
* Steinberg DA, Hurst MA, Fujii CA, Kung AH, Ho JF, Cheng FC et al (1997) Protegrin-1: a broad- spectrum, rapidly microbicidal peptide with in vivo activity, Antimicrob Agents Chemother, 41: 1738-1742.
Developed for healthcare environments, Sherwin-Williams' new Paint Shield is the first EPA-registered interior latex microbicidal paint that kills more than 99.9 percent of Staph (Staphylococcus aureus), MRSA (Methicillin-resistant Staphylococcus aureus), E.