microbicide


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microbicide

[mī′krō·bə‚sīd]
(materials)
An agent that kills microbes.
References in periodicals archive ?
Even though the idea of using a vaginal microbicide is only a theoretical possibility, it seems to have a very broad-based appeal for American women.
class="font-size--16 MsoNormal"As we pursue the rigorous requirements for an anti-HIV microbicide and contraceptive, we have already put some other lubricants in the market," Dr Peter Mwethera, the principal innovator, said.
This is the first time two phase III studies have confirmed statistically significant efficacy for a microbicide to prevent HIV.
Salim Karim that showed an ARV-based microbicide gel to be 39% effective, which are being confirmed through the FACTS 001 trial by Prof.
Archbishop Desmond Tutu said in a video link at the first-ever international conference on all HIV-related biomedical prevention research, that "No single method of prevention can end this epidemic on its own." That is why conferences on microbicides and vaccines merged to provide one single global platform to deliberate on a spectrum of biomedical prevention research for HIV.
This work revealed the tension in positive and negative aspects of microbicide gel use, including its potential to alter intimate relationships dynamics by creating suspicion of infidelity and contributing to conflict.
"In addition to the gel," said Fernandez-Romero, "we are exploring sustained-release intravaginal rings and on-demand nanofiberbased delivery systems for MZC." He stressed that developing different delivery systems for effective medications is an important step in ensuring the ultimate success of any microbicide, adding, "There is a growing demand for microbicides that prevent multiple STIs, and we are committed to ensuring that women and men have options when choosing what works most effectively for their own protection."
In the late 1980s, a few researchers began investigating the potential for Nonoxynol-9 (a widely-used spermicide) to function as a microbicide, a hypothesis ultimately rejected in 2000.
Scientists from Drexel's College of Engineering; School of Biomedical Engineering, Science and Health Systems; and College of Medicine have named the microbicide DAVEI - which stands for 'Dual Action Virolytic Entry Inhibitor.'
Since such a vaccine remains elusive, we must explore other strategies such as topical microbicide," he said.
A large-scale clinical trial evaluating whether daily use of an antiretroviral-containing oral tablet or vaginal gel can prevent HIV infection in women is being modified because an interim review found that the gel, an investigational microbicide, was not effective among study participants.