Microcephaly

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microcephaly

[‚mī·krō′sef·ə·lē]
(medicine)
The condition of having an abnormally small head, with a circumference less than two standard deviations below the mean.

Microcephaly

 

substantial reduction in skull and brain size in the presence of normal dimensions of other parts of the body. Microcephaly is accompanied by mental deficiency, from mild imbecility to idiocy. The causes of microcephaly are viral diseases suffered by the mother during the first three months of pregnancy, toxoplasmosis, and, sometimes, intrauterine meningoencephalitis of the fetus. The prognosis is unfavorable.

References in periodicals archive ?
(1,2) classified patients with microcephalic primordial dwarfism into two categories: Seckel syndrome and osteodysplastic primordial dwarfism (ODPD) that is further subdivided into three groups: I, II and III, primarily based on the skeletal characteristics.
It is in 1950 when the word "microcephalic", referred to in the dictionary entry "microcephaly", offers a not so very explicit definition: "of a small head".
A microcephalic child with neurological deficit and a sac containing cerebrum, cerebellum and brain stem structures carry a poor prognosis.
Microcephalic children can suffer developmental and intellectual difficulties that limit intelligence and muscle coordination for life.
Dobyns, "Flores hominid: new species or microcephalic dwarf?" Anatomical Record A: Discoveries in Molecular, Cellular, and Evolutionary Biology, vol.
SIH-5###6 d/ M###Seizures, hypoglycaemia###4 days###At 2 years, microcephalic with global developmental delay1 and seizures
But with the microcephalic organoid, the researchers may have figured out why microcephalic brains are smaller.
She went into spontaneous labour and delivered a premature, stillborn microcephalic fetus (weighing 1 380 g).
Eight were microcephalic, 12 were dysmorphic, 11 had coexisting epilepsy, and 9 had a cerebral palsy variant.
Among the craniofacial features studied, appearance (mongoloid facies), head (microcephalic brachycephalic) eyes (upward slanted, epicanthal folds) were the most frequent feature observed in all (100%) cases.
erectus but do fall within the range for microcephalic humans, so Holloway concludes that the fossil could have suffered from microcephaly and is not necessarily a separate species.