Frequency of microcytic anemia
in overt hypothyroid and subclinical hypothyroid patients was 20% and 18%, respectively (P = 0.618).
is most commonly caused by thalassemia, anemia of chronic disease, iron deficiency, lead poisoning, or congenital sideroblastic anemia (acronym, TAILS).
Discrimination Index of Microcytic Anemia
in Young Soldiers: A Single Institutional Analysis.
For physicians from our registry considering all limitations, an under-treatment of highly prevalent microcytic anemia
, potential iron deficient anemia has to be suspected.
Kojima et al., "Castleman-Kojima disease (TAFRO syndrome) : a novel systemic inflammatory disease characterized by a constellation of symptoms, namely, thrombocytopenia, ascites (anasarca), microcytic anemia
, myelofibrosis, renal dysfunction, and organomegaly : a status report and summary of Fukushima (6 June, 2012) and Nagoya meetings (22 September, 2012)," Journal of Clinical and Experimental Hematopathology, vol.
Laboratory studies were also obtained and showed no anomalies except for microcytic anemia
, with a normal PT/PTT and platelet count.
Even though our patient did not have overt gastrointestinal bleeding, his presentation of microcytic anemia
without colonic etiology was felt to be related to the ulcerated gastric wall metastatic lesion seen on EGD.
Nevertheless, additional laboratory tests showed progressive hematologic abnormalities revealing normal leukocyte count (7.4 x [10.sup.9]/L) with eosinophilia (1332/[micro]L), thrombocytopenia (45 x [10.sup.9]/L), and microcytic anemia
(Hb 5.0 mmol/L, MCV 76 fl).
(1) Selected common laboratory tests used to assess and differentiate microcytic anemia
can be seen in Table 1.
(14) Our patient had also microcytic anemia
, but there was no need for transfusion because of rapid response to methylene blue treatment.
They bolstered this observation with an analysis of more than 30,000 children and adolescents in the 1992-2012 National Health and Nutrition Examination Survey (NHANES) in which they found that current eczema was associated with a 1.93-fold increased odds of anemia, particularly microcytic anemia
. The underlying mechanism is unknown; however, the investigators noted that chronic inflammation and systemic immunosuppressant drugs have been shown to be associated with anemia (JAMA Pediatr.
Of the morphological variants, a higher percentage of hypochromic microcytic anemia
( n = 58, 38.7%) was observed.