microheterogeneity


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microheterogeneity

[‚mī·krō‚hed·ə·rə·jə′nē·əd·ē]
(chemistry)
A small variation in the chemical structure of a molecule that does not result in a significant change in properties.
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References in periodicals archive ?
Laurdan generalized polarization fluctuations measures membrane packing microheterogeneity in vivo.
If the slope is less than 2 for polymer blends, it may be caused by polydispersity or microheterogeneity [28].
The nugget ([C.sub.0]) represents the variability induced by microheterogeneity and experimental error, which occurs at distances smaller than the sampling intervals.
Felisberti, "Poly(vinyl alcohol) and poly(vinyl pyrrolidone) blends: Miscibility, microheterogeneity and free volume change," Polymer Journal, vol.
Egge-Jacobsen, "Mass spectrometric analysis of hepatitis C viral envelope protein E2 reveals extended microheterogeneity of mucin-type O-linked glycosylation," Glycobiology, vol.
As part of a physicochemical similarity exercise (not comparability), the authors present data on glycan microheterogeneity using hydrophilic interaction ultra-performance-liquid-chromatography (HILIC-UPLC) on three batches of Enbrel and one batch of Infinitam (Figure 3 panel b of Miranda-Hernandez et al.).
(1981) Characterization of the microheterogeneity in glycoproteins by 500 MHz [sup.1]H-NMR spectroscopy of glycopeptide preparations.
However, several factors, such as biological and individual variability as well as the structural microheterogeneity of these polypeptides, are far from being completely understood, and differences in epitope recognition have not revealed clear differences in clinical performance as evaluated by ROC analyses (2).
Molecular factors underlying the microheterogeneity of domain segregation," Biochimica et Biophysica Acta (BBA)--Biomembranes, vol.
Cooke, "Microheterogeneity of a1-acid glycoprotein: lack of discrimination between benign and malignant inflammatory disease of the lung," Clinica Chimica Acta, vol.