17] Placental malaria can produce pathological changes in the placenta, such as thickening of the basement membrane, inflammatory cell infiltrates, villitis and microinfarct
owing to clumping of parasitised red blood cells and the occlusion of micro vasculatures.
Or, TIA patients may have suffered a microinfarct
undetectable via neuroimaging with computed tomography (CAT) or magnetic resonance imaging (MRI).
pathology, dementia, and cognitive systems.
The finding of even a single microinfarct
in a non-diabetic patient is significant.
sup],,, Recently, High-resolution Magnetic Resonance was used to study the cerebral vessel in arteriosclerosis [sup], moyamoaya disease [sup] and CADASIL,[sup] microbleed and microinfarct
detection in amyloid angiopathy,[sup] the changes of perivascular spaces and perforating arteries.
DM (b) Males, and/or n % CRF, % No myocardial pathologies 14 36 50 Old MI or fibrosis 7 43 29 Recent MI 11 82 18 Recent microinfarct
10 70 40 Healing MI 6 67 50 CHF 10 40 20 Other myocardial pathologies (d) 8 50 50 Sampled Stored >6 days at 4[degrees]C prior to >72 h, death, % % No myocardial pathologies 14 29 Old MI or fibrosis 29 0 Recent MI 27 36 Recent microinfarct
40 10 Healing MI 33 17 CHF 40 20 Other myocardial pathologies (d) 38 25 No.
In addition, vulnerable plaques are more prone to microvascular changes and embolization, causing microinfarcts
and silent strokes.
were present in cerebellum, lateral thalamus, and frontal cortex.
Recent studies indicate that hypertension might potentiate the impact of Alzheimer's disease and its role in causing microbleeds, microinfarcts
, white matter disease, and multiple small strokes that might not be clinically noticeable at the time but can lead to dementia, as well as possible involvement in the accumulation of amyloid plaques in the brain (10,11).
Recent research suggests, however, that other pathologies linked with dementia--such as Lewy bodies (abnormal deposits of a protein inside brain cells), hippocampal sclerosis (a severe loss of brain cells in a key memory region called the hippocampus), microinfarcts
(small mini-strokes) and low brain weight--are also commonly present in the brains of individuals with dementia.
In Hendra virus-associated encephalitis, MRI shows similar microinfarcts
with T2/FLAIR and DWI lesions (9).
38,39) But Alzheimer's disease patients show a higher-than-normal incidence of microinfarcts
, independent of the amyloid-beta deposition in their blood vessels.