After approximately 20 cases from each subspecialty had been completed, the diagnoses obtained by each method (microscope slides
and WSI) were reviewed by one pathologist (T.W.B.), and potentially discrepant cases were identified.
Untreated glass surfaces do not provide strong enough retention for many biological samples, and this has led to the widespread adoption of positively charged hydrophobic microscope slides
for routine IHC analysis.
Luckily, antique microscope slides
covering a wide range of topics are gaining in collectible status.
We further studied sample preparation on the modified microscope slides
with regard to sensitivity and other mass spectrometric values.
The technique digitizes a glass microscope slide
, generating a virtual slide whose quality and resolution are comparable to those of a standard microscope glass slide.
Conventional approaches for creating virtual slides have relied on a well-known technique called image tiling, which requires hours to capture and "stitch together" thousands of individual small regions from a microscope slide
. With each tile, the camera has to wait for mechanical positioning instabilities to settle, and the end result contains "stitch lines" and other image artifacts that create challenges for computerized image analysis.
The Anatomical Pathology business, which is part of Thermo Fisher's Specialty Diagnostics Segment, provides microscope slides
, instruments and consumables.
By simply r inserting the adapter, a standard thermal cycler can be converted to an in situ instrument capable of accommodating up to four standard size microscope slides
with [+ or -] 0.25 C block uniformity.
Although radiologists have been using digital imaging technology for diagnostic purposes for years, technology has only recently advanced to the point that interpretation of scanned images of whole microscope slides
for primary diagnosis is feasible.
"It is thought there could be 60 forensic items, such as microscope slides
, containing material from some individuals." He added: "Investigations are being carried out urgently into this matter.
The StatSpin[R] CytoFuge 12 is a compact, low cost cytocentrifuge that concentrates up to 12 samples and gently deposits cells in a monolayer onto microscope slides
for a variety of cell preparations.